Eli Holman scored 20 points, leading five Detroit players in double figures, as the Titans beat Loyola (Ill.) 80-71 in the first round of the Horizon League tournament Tuesday night.
Third-seeded Detroit (19-13) won for the seventh time in eight games and will face sixth-seeded Youngstown State in the second round Friday night at Valparaiso, Ind.
Chase Simon scored 19, Doug Anderson 18 and Ray McCallum and Jason Calliste 10 each for the Titans, who beat Loyola for the eighth straight time.
The 10th-seeded Ramblers (7-23) got game highs of 20 points and eight rebounds from Ben Averkamp. Jordan Hicks scored 14 and Denzel Brito and Walt Gibler 12 apiece.
Loyola shot 50 percent but committed 23 turnovers to Detroit's 22.
The Titans reeled off 12 straight points for a 26-16 lead with 5:36 left in the first half and did not trail again.