Nebraska coach Tim Miles' first exposure to the Cornhuskers' rivalry with Creighton was rough on the court and on the scoreboard.
Doug McDermott scored 27 points, Gregory Echenique had 12 points and 12 rebounds, and No. 16 Creighton pulled away in the second half for a 64-42 victory Thursday night in the annual meeting of the state's top two Division I programs.
Creighton (8-1) won in Lincoln for the first time since 2004.
''It's a disappointing loss for Husker fans,'' Miles said. ''We wanted to come out and compete and make it a game to the last possession. It's still a learning process. We're trying to build our program to where we're on the other end of this outcome.''
Dylan Talley scored 14 points and Brandon Ubel had eight points and 10 rebounds to lead the Cornhuskers (6-2) in an extremely physical game at the Devaney Center.
Creighton and Nebraska were meeting for the 46th time, and the home team had won the last seven games. The Huskers lead the series 25-21.