Angelo Caloiaro had 19 points and 13 rebounds and San Francisco pulled away in overtime for an 83-81 victory over San Jose State on Wednesday night.
It was Caloairo's second consecutive double-double, and helped extend USF's winning streak to three games.
Keith Shamburger scored a career-high-tying 23 points for San Jose State (1-2).
Perris Blackwell added 18 points and six rebounds for the Dons (3-1). Rashad Green had 11 points, eight boards and five assists.
The Dons scored seven points on their first three possessions in overtime and didn't trail again, although the Spartans made it close behind Shamburger, who had eight points in the extra period.
With USF up two and 3.5 seconds on the clock, the Dons' Cody Doolin missed a pair of free throws. The Spartans' Jaleel Williams grabbed the rebound and fed James Kinney, whose 40-foot heave at the buzzer was off the mark.