Cubs 4, Astros 3(12)

Marlon Byrd's 12th-inning infield single lifted the Chicago Cubs to a 4-3 victory over the Houston Astros on Friday. Starlin Castro set up the winning rally with a leadoff walk, went to second on Darwin Barney's sacrifice, and moved to third on a wild pitch. He scored when third baseman Chris Johnson couldn't handle Byrd's dribbler up the line. Matt Garza was one strike from finishing off a five-hitter when Carlos Lee hit his second homer of the game into the left-field bleachers. The two-run shot tied the game 3-all. The Astros lost their 99th game. Houston has never lost 100 games in a season in the franchise's 50-year history.