Originally written on 5thRound.com  |  Last updated 6/2/12

On Friday, Nevada State Athletic Commission executive director Keith Kizer reported to Pro MMA Radio host Larry Pepe that heavyweight Frank Mir (Pictured) received a Therapeutic Use Exemption for Testosterone Replacement Therapy (TRT) for last Saturday’s title fight against UFC heavyweight champ Junior dos Santos.

Mir now joins the likes of fellow Octagon stars Dan Henderson, Chael Sonnen and Quinton “Rampage” Jackson as users of the controversial treatment. Nate Marquardt, who has also been prescribed TRT, was fired from the UFC when his high testosterone levels knocked him out of a bout against Rick Story just minutes before weigh-ins.

The cheater’s handbook for TRT suggests athletes are manipulating the regimen while preparing for a fight. They will jack up their testosterone levels beyond normal ranges in order to push their bodies to its outermost limit. As showtime steadily approaches, they will then taper off the treatment to get their testosterone back to a natural level – therefore, no flunked drug tests.

However, that wasn’t the case for Mir. The 33-year-old not only passed April’s random screening, but also his post-fight drug exam for UFC 146.

Ironically, Mir replaced Alistair Overeem in Saturday’s main event after “The Demolition Man” registered a Testosterone/Epitestosterone (T/E) ratio of 14:1, which is more than double the legal limit permitted by Nevada’s governing body.

Overeem is not on TRT, but allegedly injected himself with testosterone under doctor’s orders.

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