Originally posted on Football Nation  |  Last updated 8/8/13
1. Indy's Offense There are a lot of changes on the offensive side of the ball for Indianapolis. With Bruce Arians' departure, Indy hired former Standford OC Pep Hamilton. Hamilton coached both QB Andrew Luck and TE Colby Fleener at Standford. Expect Hamilton to design plays for Fleener and fellow TE Dwayne Allen frequently.2. E.J. Manuel Kevin Kolb may not even play in this game, so look for rookie QB E.J. Manuel to play most of the game. This will be Manuel's first taste of an NFL game and I expect Doug Marrone to leave him in for a large portion of it. This is another chance for Manuel to take the lead in the QB competition. Doug Marrone has already said that he is "very, very impressed" with Manuel's play in training camp, while Kolb has struggled and found himself injured.3. Buffalo's DefenseIt will be interesting to see what type of defense Buffalo plays. The secondary is going to very questionable with the absence of Pro Bowler Jairius Byrd. Mario Williams has been in and out of training camp with injuries, so I expect him to play little if at all in this game.4. Bjoern Werner Werner, a rookie, is set to replace the departed Dwight Freeney. Everyone is curious to see how this guy adapts to the NFL and whether or not he is a suitable OLB in a 3-4 defense. Keep an eye out for this guy. I think that he is somewhat of a mystery as to how well he is going to play, but it'll be fun watching him play in a game.5. Buffalo's No. 2 Receiver After Stevie Johnson, there are a list of guys trying to earn a spot at the 2nd WR position. Rookie Robert Woods might be the favorite for the 2nd spot, but that could all change if he doesn't play well. Mr. Everything a.k.a. Brad Smith has a decent shot at getting the 2nd spot as well. This is definitely something to watch for during the game.
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