Damien Comolli has left his role as Liverpool 's director of football by mutual consent, the club confirmed on Thursday morning.
The Frenchman joined Liverpool as a director of football strategy in November 2010, with his role redefined in March last year.
During that time he has overseen a number of high-profile signings, including the club-record £35million acquisition of Andy Carroll from Newcastle, while he also survived a change of manager when Kenny Dalglish returned to the club to replace Roy Hodgson.
His time at Anfield has come to an end now, though, with a club statement from principal owner John Henry reading: "We are grateful for all of Damien's efforts on behalf of Liverpool and wish him all the best for the future."
Chairman Tom Werner added: "The club needs to move forward and we now have a huge game on Saturday.
It is important that everyone joins us in supporting the manager and gets behind Kenny and the team and focuses on a strong finish to the season."