Manchester United boss Sir Alex Ferguson expects Paul Scholes to be missing for another fortnight with a knee injury.
The United veteran has been struggling with the problem and sat out the midweek trip to Real Madrid .
And Ferguson revealed Scholes will not be available for Monday's FA Cup tie with Reading.
"It is a knee injury, which has been bothering him a bit," said Ferguson.
"We have tried another treatment during the week.
"He will probably be back in another couple of weeks."
Ferguson confirmed his squad had come through their midweek exertions without a problem, but that there would be changes to his starting line-up against Brian McDermott's progressive team.
"I will make some," he said.
"We want to get to the quarter-finals and we do expect to qualify."
Ferguson also had words of praise for David de Gea, who produced possibly his best performance for United in the 1-1 Bernabeu draw with a string of fine saves.