Alex Karaban scored a game-high 21 points and Stephon Castle added 15 to lead six players in double figures and help top-ranked UConn roll past host DePaul 101-65 on Wednesday in Chicago.
Cam Spencer added 14 points to help the Huskies (23-2, 13-1 Big East) win their 13th consecutive game. Jaylin Stewart followed with 11 points, while Tristen Newton and Donovan Clingan each had 10.
The Blue Demons have lost 25 straight conference games overall and 17 in a row against the Huskies. Jaden Henley paced DePaul (3-21, 0-13) with 15 points. The Blue Demons trailed by as many as 39 and have lost five in a row by at least 23 points.
K.T. Raimey scored 12 points for the Blue Demons and Elijah Fisher chipped in 10.
Castle and Karaban combined on 13-for-20 shooting to help the Huskies eclipse the 100-point mark for the first time in conference play this season. UConn shot 56.3 percent compared to 40.7 percent for DePaul.
Karaban went 5-for-8 from deep. Stewart connected on three straight treys over a 1:55 span early in the second half. The Huskies had a plus-16 advantage on the glass, with Newton snagging eight rebounds.
The Blue Demons remained without leading scorer Chico Carter Jr., who has missed the past seven games with a rib injury. Jalen Terry had 10 assists.
DePaul took its second and final lead of the night on a Churchill Abass layup with 18:27 remaining in the first half. The Huskies regained the advantage with a Spencer jumper on the ensuing possession and never relinquished it.
UConn led by as many as 26 points in the first half, seizing control with a 9-0 run.
DePaul didn't reach double figures until a Henley layup at the 10:07 mark of the first half.
Karaban (12 points), Spencer (nine), and Hassan Diarra (eight) led a balanced UConn attack in the first half.
The Huskies rolled to 17-for-31 (54.8 percent) shooting to take a 52-29 lead into the break. Karaban was especially efficient, going 3-for-6 from the floor and connecting on each of his four free-throw attempts.
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