© Kirby Lee-USA TODAY Sports

INDIANAPOLIS - While the annual NFL Scouting Combine is not the be-all and end-all when it comes to critiquing prospects for the NFL Draft, it is a critical component of the entire draft process. A great performance can serve as a massive boost to a player's overall draft stock, and at the 2024 iteration of the event, Isaac Guerendo certainly made himself some money.

The former Louisville running back put together a phenomenal outing at Lucas Oil Stadium in Indianapolis. Not only was he arguably the top performer amongst the running backs invited to this year's combine, he put together one of the best all-around performances out of a running back in the history of the NFL Combine.

In the combine's marquee event, the 40-Yard Dash, Guerendo posted a blazing 4.33 official time with a 1.55 10-Yard Split. Not only was his 40-time the best among all running backs, it tied Toledo cornerback Quinyon Mitchell for the second-best through the first three days of the combine, behind only Clemson cornerback Nate Wiggins' 4.28 time. 

The 40-Yard Dash wasn't the only drill where Guerendo put on display his athleticism. He also logged a 41.5" in the vertical jump, as well as a 10' 9" in the broad jump. His vertical led all running backs and was fifth overall through three days of combine drills, while his broad jump was second to Tennessee's Jaylen Wright (11' 2") amongst running backs and tied for 15th overall.

Guerendo measured 6-foot and 221-pounds at the combine, along with 30.75' arms and 9.25" hands. Put together his measurables along with his results in the combine drills, and it produces an insane Relative Athletic Score of 9.98. Since 1987, it was the best RAS score from a running back since Houston's Jackie Battle posted a 9.99 in 2007, and it tied Miami's Edgerrin James and Tennessee's James Stewart for third-best at the position. USC's Justin Fargas posted the lone perfect 10.00 back in 2003.

Joining Louisville as a transfer from Wisconsin last offseason, the 6-foot-1, 225-pound back was the primary backup running back behind Jawhar Jordan for the 2023 season. When Jordan was hampered by a hamstring injury in the second half of the season, Guerendo saw his role in the offense increase dramatically, to which he took full advantage.

In the final six games of the year, Guerendo's combination on speed and power was on full display, rushing 72 times for 558 yards (7.75 YPC average) and eight touchdowns. This included four games with over 90 rushing yards, and a 161-yard and three-touchdown performance against USC in the Holiday Bowl.

He finished the season with 810 yards and 11 touchdowns on 132 rushes, along with 22 receptions for 234 yards to total 1,044 yards from scrimmage. Guerendo was also Louisville's leading kick returner, logging 11 returns for 211 yards.

More must-reads:

TODAY'S BEST
Watch: Robert MacIntyre claims emotional first PGA Tour win with dad as caddy
Watch: Shuttered college's baseball team's magical run ends on walk-off HR
Commanders release kicker Brandon McManus following his lawsuit
Giants ace Blake Snell's season just went from bad to worse on Sunday
Yuka Saso rallies to win her second U.S. Women's Open
Ryan Blaney's misfortune is Austin Cindric's gain after wild final lap at Gateway
Tigers to promote outfielder with stellar batting eye
Watch: Austin Cindric wins at Gateway after Ryan Blaney runs out of fuel on final lap
Report: NFL expected to reach resolution on Eagles', Falcons' tampering cases this week
White Sox's Tommy Pham voices frustrations in profane interview
Blue Jays GM has no interest in entertaining trade offers for star players
Yankees' Aaron Boone reveals rehab assignment date for ace pitcher
Dustin Poirier teases retirement following his loss to Islam Makhachev at UFC 302
Watch: Orioles slugger Gunnar Henderson clobbers 19th homer vs. Rays
11 NFL teams gain cap space from post-June 1 cuts
WNBA upgrades hard foul on Caitlin Clark to a Flagrant 1
Three takeaways as Panthers eliminate Rangers, advance to Stanley Cup Final
Corey Heim dominates at Gateway for fourth Truck Series win of 2024 season
Mets honor Darryl Strawberry in fitting fashion during number retirement ceremony
Phillies ace leaves game after taking 106 mph comebacker to hand