Watch: Syracuse vs. Louisville Full Game | 2021 ACC Football

Louisville had it clicking on all cylinders against Syracuse, winning 41-3. Cardinals quarterback Malik Cunningham threw for 209 yards and 4 touchdowns and rushed for a touchdown as well in the win. Jalen Mitchell rushed for 102 yards for the Cardinals, and Ahmari Huggins-Bruce caught 2 touchdown passes from Cunningham. Syracuse’s offense was stifled all day, but Sean Tucker managed 95 yards rushing on 19 carries in the loss.