Kamil Krzaczynski-USA TODAY Sports

Brandon Drury and Matt Thaiss connected for back-to-back home runs in the first inning and went on to combine for five hits and four RBIs to power the visiting Los Angeles Angels to a 6-4 win against the Chicago White Sox on Monday night.

Drury and Thaiss delivered against White Sox starter Michael Kopech. Drury's three-run shot opened the scoring.

Mike Trout added two hits and an RBI for the Angels, who overcame 16 strikeouts to send the White Sox to their fourth loss in five games.

Angels closer Carlos Estevez worked around an Eloy Jimenez solo homer, a hit batsman and a walk in the ninth to earn his 13th save in as many chances.

Los Angeles capitalized on control issues from Kopech to create the early scoring opportunity, as Trout walked and Shohei Ohtani was hit by a pitch with one out. A two-out wild pitch later in the inning allowed the Angels stars to advance to second and third before Drury went deep.

Chicago got a run back in the bottom half of the frame, as Jimenez lined an RBI single to center with two outs.

Home runs helped the White Sox draw closer. Andrew Vaughn (two hits) sent an opposite-field homer to right in the fourth inning before Romy Gonzalez opened the fifth with another solo shot against Angels starter Griffin Canning.

Kopech matched a season high with 10 strikeouts despite pitching a season-low 4 1/3 innings. He allowed four runs on five hits while scattering two walks and two hitting two batters to fall to 3-5.

Canning (4-2) allowed three runs and six hits in six innings with zero walks and nine strikeouts.

White Sox closer Liam Hendriks was reinstated to the active roster before the game. The 34-year-old Hendriks was diagnosed with stage 4 non-Hodgkin's lymphoma in December and underwent his final round of chemotherapy four months later.

Hendriks allowed a pair of runs in the eighth, scattering three hits and a walk. The Angels scored runs on a sacrifice fly and a single off the glove of leaping shortstop Tim Anderson.

More must-reads:

TODAY'S BEST
Watch: 150th Kentucky Derby ends in three-horse photo finish
Watch: Anthony Edwards does it all for Minnesota
Clippers could see nine-time All-Star jump ship this summer
Phillies get rough injury news on Trea Turner
Watch: Yankees star Aaron Judge receives first career ejection after arguing called third strike
Mavericks lose key player for 'significant period of time'
Blue Jays manager John Schneider blasts team after latest loss
Lakers make another big change after firing Darvin Ham
Draymond Green doubles down on Knicks' inability to win a championship
Phillies lose two-time All-Star to injured list
NBA announces punishment for Lakers star over actions in elimination game
Heat may be cooling on Jimmy Butler's long-term future
NFL insider defends former Steelers QB Kenny Pickett from 'bust' label
Nuggets may miss this player as postseason run continues
Report: Russell Westbrook situation 'far more challenging' than previously thought
Kansas City Chiefs release former second-round pick at WR
NHL announces finalists for 2024 Lady Byng Trophy
Giannis Antetokounmpo refutes claim by HC Doc Rivers
Former Pro Bowler attempting comeback with NFC East team after two seasons out of action
Vikings' J.J. McCarthy wanted one team to draft him

Want more sports news?

Join the hundreds of thousands of fans who start their day with Yardbarker's Morning Bark, the best newsletter in sports.