Nick Turchiaro-USA TODAY Sports

Matt Chapman hit two home runs and had three RBIs and the Toronto Blue Jays defeated the visiting Detroit Tigers 5-3 Thursday night.

Willi Castro and Jonathan Schoop hit solo home runs for the Tigers in the opener of a four-game series.

Toronto left-hander Yusei Kikuchi (4-5) was reinstated from the 15-day injured list (neck strain) to make the start. He allowed one run, two hits and one walk while striking out five in five innings.

Detroit left-hander Tyler Alexander (2-4) allowed three runs (two earned), five hits and one walk with one strikeout in four innings.

Castro hit his third home run of the season on a drive to right center with two out in the second.

George Springer reached first base with one out in the third on a throwing error by Javier Baez on a grounder to shortstop. He took second on a groundout and scored on Alejandro Kirk's broken-bat single.

Lourdes Gurriel Jr. singled with one out in the fourth and Chapman followed with a home run to left.

Angel De Jesus allowed Chapman's 18th home run of the season with one out in the bottom of the sixth.

Schoop hit his seventh home run of the season on a drive to left against Tim Mayza with one out in the seventh.

Jose Cisnero replaced DeJesus with one out and runners at the corners in the bottom of the seventh and induced a double-play grounder from Teoscar Hernandez.

Victor Reyes led off the eighth with a double against Yimi Garcia. Reyes held second when shortstop Bo Bichette was charged with an error on Robbie Grossman's popup. Baez walked.

Eric Haase hit a sacrifice fly with one out and Jordan Romano replaced Garcia to end the inning on a groundout.

Alex Lange allowed an unearned run in the bottom of the eighth started by third baseman Jeimer Candelario's throwing error. A walk and a sacrifice set up Danny Jansen's sacrifice fly.

Romano pitched a perfect ninth to earn his 22nd save.

Detroit put left-hander Andrew Chafin on the restricted list Thursday because was not vaccinated against COVID-19 and could not enter Canada. Right-hander Bryan Garcia was selected from Triple-A Toledo as a replacement.

Toronto optioned right-hander Jeremy Beasley to Triple-A Buffalo.

More must-reads:

TODAY'S BEST
Mavs get good news on Maxi Kleber ahead of Game 4
Patriots exec discusses team's approach to QB competition
Braves to promote No. 3 prospect for MLB debut Wednesday
Diamondbacks release veteran infielder
Packers' former first-round pick planning to make 'monster leap'
NFLPA finalizing proposal for major change to offseason schedule
LeBron James shouts out Jaylen Brown after Celtics advance to NBA Finals
Pacers collapse down the stretch as Celtics sweep ECF
Hall of Famer, beloved broadcaster Bill Walton dead at 71
Jason Robertson leads Stars to comeback win over Oilers in Game 3
Despite recent form, Rafael Nadal's legacy is still gold standard for tennis
Bengals coach offers significant injury update on QB Joe Burrow
MLB officials expect automated ball-strike system to be implemented in 2026
Vikings reportedly considered Justin Jefferson trade during NFL Draft
A matured Kyrie Irving is finally proving to be the star we all knew he could be
Insider: Sixers 'a threat' to sign LeBron James in free agency
Week 14 NASCAR rankings: Larson's no-show shakes up the running order
Three hitters Braves should target after losing Ronald Acuna Jr.
Shohei Ohtani shares major update on his pitching rehab
Status of Pacers' Tyrese Haliburton revealed for Game 4 of ECF