Eric Canha-USA TODAY Sports

Corbin Burnes allowed two hits in seven innings as the Baltimore Orioles spoiled the Boston Red Sox's home opener by earning a 7-1 victory Tuesday.

Burnes (2-0) struck out six, walked two and lowered his ERA to 1.93. He did not give up a hit after the first inning.

Colton Cowser hit two doubles and drove in four runs. The loss ended Baltimore's two-game losing streak.

Tyler O'Neill hit a solo home run for Boston. It was his sixth home run in 10 games. Boston's only other hit was a Triston Casas single in the first inning.

Boston starter Brayan Bello (1-1) left the game with one out in the sixth and Boston trailing 3-1. He allowed one earned run on four hits, walked two and struck out three.

O'Neill's two-out homer opened the scoring in the bottom of the first, but the Orioles tied the game when Cowser's double to center scored Cedric Mullins in the second.

Baltimore took a 3-1 lead by scoring a pair of unearned runs in the third. After Ryan Mountcastle's infield single, Mullins reached on a two-base error by left fielder Jarren Duran. Both runners scored on Cowser's two-out double.

The Orioles added a run in the seventh to make it 4-1. Gunnar Henderson doubled with two outs, stole third and scored on Adley Rutschman's single up the middle.

The lead grew to 5-1 in the eighth when Cowser's sacrifice fly allowed Ryan O'Hearn to score, and Baltimore scored two more runs in the ninth. Anthony Santander's RBI single drove in Henderson, and Rutschman scored on a Mullins single to center.

Baltimore's final four runs were charged to reliever Josh Winckowski, who entered the game with one out in the seventh.

Henderson, Rutschman and Mullins also had two hits in the victory. The Orioles outhit the Red Sox 13-2. Baltimore pitching recorded 10 strikeouts.

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