Nathan Ray Seebeck-USA TODAY Sports

Two highly touted National League West teams currently under .500 get an opportunity to continue a recent upward trend at the other's expense when the visiting Arizona Diamondbacks and the San Francisco Giants open a four-game series on Thursday.

Both teams have won three of five entering the series. The Diamondbacks are kicking off a 10-game trip, while the Giants are opening a 10-game homestand.

The Diamondbacks enter the series coming off a 5-3 home loss to the Chicago Cubs on Wednesday. Ketel Marte had a single, a double, a home run and two RBIs in the defeat.

The other Arizona run was the product of a Joc Pederson homer on the eve of his return to San Francisco. Pederson hit just .235 with 15 home runs for the Giants last season.

After playing 37 of his 121 games in the outfield for the Giants in 2023, the veteran has settled into a designated hitter role for the Diamondbacks. He has hit .355 in 13 games as a DH this season.

Pederson drew interest from the Diamondbacks in the offseason because of their issues with right-handed pitching last season. Pederson, a left-handed batter, has had all but three of his plate appearances against right-handers this year, and he is hitting .323 against righties.

He entered the Wednesday game as a sixth-inning pinch hitter against a right-hander, then homered in the ninth against Cubs left-hander Drew Smyly.

"I don't really look at numbers much," Peterson said. "I like to get with the hitting coach and figure out the best game plan to win that one at-bat."

Pederson is expected to be back in the starting lineup Thursday with the Giants scheduled to throw right-hander Logan Webb (1-1, 3.80 ERA), who has had the upper hand in career head-to-heads. Pederson has gone just 2-for-7 against Webb, but does also have a walk and a hit by pitch in 10 plate appearances.

Webb had his best outing of the season in his most recent start, an 11-2 win at Tampa Bay last Saturday in which he allowed just one run in seven innings. The 27-year-old has made 10 previous starts against the Diamondbacks, going 5-3 with a 2.80 ERA. He beat them 8-5 and 4-2 in head-to-heads at home last season.

The Giants took two of three in Miami to begin the week, earning the series win via a 3-1 decision over the Marlins on Wednesday. Kenton Winn worked six strong innings on a day when the Giants did not homer for the ninth time this season. Six of those nine occurred in succession on their last homestand against the San Diego Padres and Washington Nationals.

Giants manager Bob Melvin walked away from the latest victory hoping winning leads to more hitting, not necessarily vice versa.

"To get out of these little funks that we're in, it usually takes a little bit of a winning streak," he said. "Confidence rises and you're able to gain some momentum. We just haven't had a ton of traction as far as that's gone yet."

Ryne Nelson (1-2, 5.27 ERA) will be the man tasked with continuing the Giants' offensive struggles. The 26-year-old right-hander has faced San Francisco three times (all starts) in his career, going 1-0 with a 3.44 ERA.

Nelson recorded his lone win of the season in his most recent start, a 4-2 home victory over the St. Louis Cardinals on Saturday. He allowed just one run on seven hits in six innings while striking out four and walking one.

More must-reads:

TODAY'S BEST
Watch: Dodgers' Shohei Ohtani blasts HR where he created '50-50' club
Islanders climb nine spots to No. 1 pick with stunning lottery win
Oilers get good news and bad news on Mattias Ekholm
Why Cavs HC Kenny Atkinson might not want to celebrate COY win
Ravens downplay Justin Tucker's release with a tone-deaf statement
Astros place key slugger on injured list
Michigan HC Sherrone Moore to be suspended two games
'It makes sense': Steelers see new Aaron Rodgers conspiracy theory emerge as team waits for 2025 decision
Marc-Andre Fleury joining Canada for World Championship
One-time All-Star pitcher announces retirement
Kings, GM Rob Blake mutually part ways
Buddy Hield lifts Warriors to massive Game 7 win over Rockets
Jazz agree to long-term extension with HC Will Hardy
Patriots legends rip Giants' Abdul Carter over Lawrence Taylor number request
LSU coach makes big guarantee about what Will Campbell will offer Patriots
Warren Moon has strong message for Shedeur Sanders
Jordan Spieth has sobering take on Scottie Scheffler
Watch: Jets eliminate Blues in instant classic double OT Game 7 win
Pacers use balanced attack vs. Cavaliers to steal home-court advantage
Fever's Caitlin Clark dazzles in preseason debut vs. Brazil

Want more MLB news?

Join the hundreds of thousands of fans who start their day with Yardbarker's Morning Bark, the best newsletter in sports.