The Octagon is back inside the UFC Apex in Las Vegas this weekend for another fight card as UFC On ESPN 51: Luque vs. Dos Anjos goes down inside of the UFC's home base.

The card is headlined by a welterweight showdown as Vicente Luque takes on former UFC Lightweight Champion Rafael Dos Anjos. Luque is fighting for the first time in a year as he looks to end a two-fight losing skid, having lost to Belal Muhammad and Geoff Neal. Dos Anjos is making another run in the welterweight division as he looks for his second straight win following a submission of Bryan Barberena in December.

In the co-main event, it's an exciting featherweight match-up as longtime veteran Cub Swanson takes on Hakeem Dawodu. Also on the main card is a light heavyweight battle between Khalil Rountree and Chris Daukaus, a women's strawweight fight pitting Polyana Viana against Iasmin Lucindo, and a pair of middleweight bouts as AJ Dobson fights Tafon Nchukwi, and Josh Fremd takes on Jamie Pickett.

ESPN PRELIMS | 4 PM ET/1 PM PT

> Women's Flyweights- Juliana Miller (3-2, 1-1 UFC) vs. Luana Santos (5-1, 0-0 UFC)

> Bantamweights- Da'Mon Blackshear (13-5-1, 1-1-1 UFC) vs. Jose Johnson (15-7, 0-0 UFC)

> Women's Strawweights- Jaqueline Amorim (6-1, 0-1 UFC) vs. Montserrat Conejo (10-2, 1-1 UFC)

> Heavyweights- Josh Parisian (15-6, 2-3 UFC) vs. Martin Buday (12-1, 3-0 UFC)

> Featherweights- Francis Marshall (7-1, 1-1 UFC) vs. Isaac Dulgarian (5-0, 0-0 UFC)

> Lightweights- Terrance McKinney (13-6, 3-3 UFC) vs. Mike Breeden (10-5, 0-2 UFC)

> Bantamweights- JP Buys (9-5, 0-3 UFC) vs. Marcus McGhee (7-1, 1-0 UFC)

ESPN MAIN CARD | 7 PM ET/4 PM PT

> Middleweights*- Josh Fremd (10-4, 1-2 UFC) vs. Jamie Pickett (13-9, 2-5 UFC)

*Fremd missed weight by three pounds

> Middleweights*- AJ Dobson (6-2 1 NC, 0-2 UFC) vs. Tafon Nchukwi (6-3, 2-3 UFC)

*Nchukwi missed weight by 3.5 pounds

> Women's Strawweights- Polyana Viana (13-5, 4-4 UFC) vs. Iasmin Lucindo (14-5, 1-1 UFC)

> Light Heavyweights- #13 Khalil Rountree (11-5 1 NC, 7-5 1 NC UFC) vs. #14 HW Chris Daukaus (12-6, 4-3 UFC)

> Featherweights- Cub Swanson (28-13, 12-9 UFC) vs. Hakeem Dawodu (13-3-1, 6-3 UFC)

> Welterweights- #10 Vicente Luque (21-9-1, 14-5 UFC) vs. #9 LW Rafael Dos Anjos (32-14, 21-12 UFC)

More must-reads:

TODAY'S BEST
Pacers' Pascal Siakam leads team to Game 6 win vs. Knicks
Late goal sends Panthers to Eastern Conference Finals
Ex-teammate of Shohei Ohtani placed bets with same illegal bookmaker as interpreter 
Former Rams first-round pick retires from NFL after 11 seasons
Insider provides major injury update on Celtics' Kristaps Porzingis
Watch: Bruins strike first in Game 6 with incredible backhand goal
Dodgers make series of moves involving notable players
Giants rookie CF to undergo season-ending labrum surgery
Hurricanes not expected to re-sign defenseman, center
Paul Skenes makes incredible Wrigley Field history in second-career MLB start
Maple Leafs tab former Stanley Cup winner as new head coach
NFL insider expands on competition between Steelers QBs Russell Wilson, Justin Fields
NFL sets outrageous prices for Eagles-Packers Brazil game
Scottie Scheffler shoots improbable 66 after warming up for PGA Championship in a jail cell
Nuggets star has worrying comment about latest injury
Broncos 'very unlikely' to bring back former NFL interceptions leader
Greg Olsen offers broadcasting advice to Tom Brady
Yankees' Juan Soto reacts to Hal Steinbrenner contract talk
Mets star has theory about closer Edwin Diaz's recent struggles
Scottie Scheffler arrested, still makes PGA Championship tee time