The Denver Broncos are set to host the San Francisco 49ers at Empower Field at Mile High in Denver, Colorado, on Sunday, September 25 at 5:20 p.m. PT. Each week, the 49ers Webzone staff predicts the winner within its annual NFL Pick 'em contest. That includes writers and forum moderators.
This week, five of six participating staff members selected the 49ers to beat the Broncos. San Francisco is currently a 1.5-point favorite.
As for all the fans who are taking part in our NFL Pick 'em contest, 87 percent have the 49ers winning the game, as of this post. That's the lowest percentage picking the Niners this season but still overwhelmingly in their favor.
Of all the Week 3 game predictions, the most lopsided results comes from Sunday's matchups between the Kansas City Chiefs and the Indianapolis Colts, and the Jacksonville Jaguars and Los Angeles Chargers. Voting has 97 percent of fans believing the Chiefs and Chargers will earn the victories.
When it comes to the predictions, the closest matchup is between the Atlanta Falcons and the Seattle Seahawks on Sunday, with 56 percent selecting the Seahawks to win the game.
Below is a breakdown of all 16 matchups for the upcoming slate of NFL games.
| Picks | Away | Home | Picks |
|---|---|---|---|
| 39% | Texans | Bears | 61% |
| 62% | Raiders | Titans | 38% |
| 97% | Chiefs | Colts | 3% |
| 88% | Bills | Dolphins | 12% |
| 14% | Lions | Vikings | 86% |
| 83% | Ravens | Patriots | 17% |
| 88% | Bengals | Jets | 12% |
| 93% | Eagles | Commanders | 7% |
| 76% | Saints | Panthers | 24% |
| 3% | Jaguars | Chargers | 97% |
| 80% | Rams | Cardinals | 20% |
| 44% | Falcons | Seahawks | 56% |
| 31% | Packers | Buccaneers | 69% |
| 87% | 49ers | Broncos | 13% |
| 35% | Cowboys | Giants | 65% |
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