Nick Bosa appears to have suffered a serious leg injury. Kyle Terada-USA TODAY Sports

San Francisco 49ers defensive end Nick Bosa was carted off early in Sunday’s game against the New York Jets with what appeared to be a knee injury.

Bosa looked like he got rolled up on while making a tackle earlier in the first half. He immediately clutched his left knee in pain.

Bosa, the No. 2 overall pick in last year’s draft, won the Rookie of the Year following a season in which he had nine sacks, 47 tackles and a forced fumble. He’s one of the most important pieces of the 49ers defense and would be extremely difficult to replace. Hopefully the injury is not as serious as it looked.

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