San Francisco 49ers defensive end Clelin Ferrell. Darren Yamashita-USA TODAY Sports

One San Francisco 49ers defender’s postseason is over before it even began.

Ian Rapoport of NFL Network reported Saturday that the Niners have put defensive lineman Clelin Ferrell on injured reserve with a knee injury, thus ending his season. San Francisco is activating safety George Odum off IR in a corresponding move.

Ferrell, a former first-round pick, had already been ruled out earlier in the week for Saturday’s divisional playoff game against the Green Bay Packers. It is a sizable blow for the Niners as Ferrell had started all 17 regular-season games for them, recording 3.5 sacks and a career-high 13 QB hits.

The No. 1-seeded Niners will still be heavily favored to take care of business against the Packers regardless though. This may also be the opportunity for the former champion defensive lineman who San Francisco recently signed to really make his mark.

More must-reads:

TODAY'S BEST
Phil Foden lifts Manchester City to fourth consecutive English Premier League title
Dodgers add recently acquired left-hander to active roster
Report: 2023 No. 7 pick expected to terminate KHL contract, join Flyers
Mavericks advance to Western Conference Finals aided by controversial call late
Connor McDavid, Oilers hammer Canucks to force Game 7
Tyson Fury-Oleksandr Usyk epic increases excitement for potential rematch
Seize the Grey wins in muddy Preakness
Even Mike Budenholzer admits the Suns need a point guard
Watch: Juan Soto's first multi-homer game as a Yankee
Xander Schauffele, Collin Morikawa lead at PGA Championship
Knicks could get major boost for Game 7 showdown with Pacers
Giants All-Star pitcher suffers setback in recovery from injury
Panthers star named winner of 2024 Selke Trophy
WNBA to investigate $100,000 sponsorship deals for Aces players
Tiger Woods blames one big factor for missing the cut at PGA Championship
'Ain't good enough': Draymond Green claims Celtics must 'win it all' or it's a 'failure'
Blue Jays GM wants struggling club to feel 'massive sense of urgency'
Raptors expected to flip former NBA champion during the offseason
MLB insider reveals Mets' massive extension offer that Pete Alonso turned down
Celtics legend provides update after gruesome finger injury