Arizona Cardinals vs. Los Angeles Rams odds and best bets

These are two good teams, the question is how good? Arizona was the best team in the NFL in the first half of the season, but they faded down the stretch. 

That enabled the Rams to ultimately win the NFC West, however, I think this team never really reached the potential that some saw for it when they made the big offseason move to bring in QB Matt Stafford via trade.

These division foes met twice during the regular season with the home team winning each time. That does give some advantage to the Rams, but Arizona was 8-1 on the road this season. That impressive mark should give them plenty of confidence to come to SoFi Stadium and try to knock off the Rams. 

Game Info:

Arizona Cardinals (11-6) vs. Los Angeles Rams (12-5)
Monday, January 17, 2022
8:15 PM
SoFi Stadium, Los Angeles, California
ESPN

Betting Odds (as of Friday, January 14th)
Spread Cardinals +4 (-110), Rams -4 (-110)
Total: 49.5
Moneyline: Cardinals +161, Rams -194

Bets I Like

Arizona Cardinals +4 (-110)

I love the value on the Cardinals to win outright but at this number, the spread just makes more sense. When these teams met in L.A. during the season it was tied at halftime. Kyler Murray threw a couple of picks in the game while Stafford was turnover-free, that was the big difference. If Arizona cleans it up, they will be in this game until the final possession.

Kyler Murray Most Passing Yards (+100)

In both of the games these teams played this season, the losing team threw for more yards than the winning team. That makes sense the way that teams often completely abandon the run as they play catchup. The oddsmakers are saying the Cardinals are supposed to lose and will be in that situation on Sunday. Getting even money on this bet is a great value. Murray passed for 344 yards the last time these teams played, the highest output of either quarterback against the other this season.

Arizona Over 22.5 Points Scored (-110)

Arizona finished the season averaging just under 27 PPG. In the two games against L.A. this season, they scored 23 and 37 points, so I was surprised to see this number set where it is. The Rams defense has been overrated all year, and while it is capable, I do not see them shutting down Arizona, win or lose. Arizona is going to move the ball and score some points. They have lots of weapons and know they need to score to have a chance. They are not built to win 17-14 games.