Tina MacIntyre-Yee/Rochester Democrat and Chronicle / USA TODAY NETWORK

The Buffalo Bills ruled out linebacker Matt Milano for the rest of Sunday's game against the Jacksonville Jaguars due to a knee injury.

Milano was one of at least three Buffalo defenders to sustain an injury in the first quarter of the game in London.

Defensive tackle DaQuan Jones (pectoral) was deemed doubtful to return. Defensive end Kingsley Jonathan also had to be helped off the field with an undisclosed injury.

Milano appeared to have his right leg caught in a pile of players early in the game. He had to be helped off the field and was ruled out before the first quarter ended.

Milano, 29, was a Pro Bowl and first-team All-Pro selection in 2022. He had 27 tackles and a forced fumble through the first four games of this season.

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