USA TODAY Sports

The 49ers won't be fully healthy when the playoffs start for them in a week and a half.

Clelin Ferrell has a knee injury and will miss at least one game, possibly a few, according to head coach Kyle Shanahan. He said it's possible Ferrell will return in the playoffs, meaning it's not certain he will return.

Ferrell injured his knee early in the 49ers' meaningless season finale against the Rams. Head coach Kyle Shanahan played the starters in the first quarter so they wouldn't be rusty for the playoffs -- a smart decision, but one that came with inherent risk because football is violent. It was likely that one starter would get injured, and that starter was Ferrell.

Ferrell is one of the few 49ers starters who isn't a Pro Bowler or a Pro Bowl alternate this season, because he has only 3.5 sacks. But he was extremely reliable and consistent against the run for 17 regular season games.

Ferrell is one of the 49ers' best run defenders. He arguably is their best edge-setter -- better than Nick Bosa and Chase Young, who both think pass rush before run defense. So Ferrell's absence could hurt the 49ers if they play a team that runs the ball well, a team such as the Rams or the Lions.

There's a distinct possibility the 49ers will play the Rams after the first-round bye week, and the Rams have Kyren Williams, the second-leading rusher in the NFL. Having Arik Armstead return from plantar fasciitis certainly would help the 49ers' interior run defense, but Williams also attacks around the edges, where Ferrell would be.

It will be interesting to see what the absence of the 49ers' least-heralded defensive end will impact the defense.

More must-reads:

TODAY'S BEST
Phil Foden lifts Manchester City to fourth consecutive English Premier League title
Dodgers add recently acquired left-hander to active roster
Report: 2023 No. 7 pick expected to terminate KHL contract, join Flyers
Mavericks advance to Western Conference Finals aided by controversial call late
Connor McDavid, Oilers hammer Canucks to force Game 7
Tyson Fury-Oleksandr Usyk epic increases excitement for potential rematch
Seize the Grey wins in muddy Preakness
Even Mike Budenholzer admits the Suns need a point guard
Watch: Juan Soto's first multi-homer game as a Yankee
Xander Schauffele, Collin Morikawa lead at PGA Championship
Knicks could get major boost for Game 7 showdown with Pacers
Giants All-Star pitcher suffers setback in recovery from injury
Panthers star named winner of 2024 Selke Trophy
WNBA to investigate $100,000 sponsorship deals for Aces players
Tiger Woods blames one big factor for missing the cut at PGA Championship
'Ain't good enough': Draymond Green claims Celtics must 'win it all' or it's a 'failure'
Blue Jays GM wants struggling club to feel 'massive sense of urgency'
Raptors expected to flip former NBA champion during the offseason
MLB insider reveals Mets' massive extension offer that Pete Alonso turned down
Celtics legend provides update after gruesome finger injury

Want more 49ers news?

Join the hundreds of thousands of fans who start their day with Yardbarker's Morning Bark, the best newsletter in sports.