Colts' Darius Leonard, Anthony Castonzo won't play vs. Browns

The 3-1 Indianapolis Colts will be without starting left tackle Anthony Castonzo and linebacker Darius Leonard against the 3-1 Cleveland Browns on Sunday due to injuries. 

Andrew Walker of the club's official website explained that Castonzo is dealing with a rib issue. Leonard, an All-Pro, is carrying a groin injury. Per Mike Wells of ESPN, neither man practiced during the week. 

Le'Raven Clark, selected by the Colts in the third round of the 2016 NFL Draft, will take Castonzo's place on the offensive line. He'll start opposite Cleveland's Myles Garrett, one of the league's top pass-rushers. 

Garrett, 24, is tied for the NFL lead in sacks with five in four outings. Two of those came in last week's thrilling 49-38 road win at the Dallas Cowboys. 

Colts head coach Frank Reich spoke about this particular challenge on Friday. 

"With Myles Garrett and what they do defensively, they move him around," Reich explained. "I'm sure he'll switch sides. That's nothing new for him. They'll want to test out Le'Raven. We have our plans on how we'll handle those things. We go into every week with a protection plan no matter who we're playing."

Indianapolis also listed linebacker Anthony Walker as questionable after he was limited in Friday's practice because of an ankle injury. 

Cleveland begins the weekend atop the NFL in rushing yards per game (204.5) but will be without starting running back Nick Chubb. The Browns placed Chubb on injured reserve earlier this week with a sprained MCL.