Philadelphia Eagles offensive guard Isaac Seumalo (73) will miss at least three weeks. Eric Hartline-USA TODAY Sports

The Eagles can’t catch a break. On Monday, head coach Doug Pederson announced that starting left guard Isaac Seumalo has been placed on injured reserve with a knee injury. 

Per league rules, Seumalo will miss at least the next three weeks. This was the outcome the Birds feared after the interior lineman went down in the second quarter against the Rams. After his early exit, Matt Pryor moved into his spot, and he profiles as the likely LG replacement in the interim.

The Eagles’ bad luck on the O-Line began this summer when star guard Brandon Brooks was lost for the season. Fortunately, they had old friend Jason Peters on speed dial, and he was ready to return and change positions to help fill the gap. Then, the injury bug bit Andre Dillard, pushing Peters back to his native spot at left tackle.

As the Eagles move ahead with yet another new front five, there is at least one silver lining: Seumalo’s injury does not appear to be a season-ender. But, at the very least, they’ll be without the 26-year-old (27 in October) for the next three games against the Bengals, 49ers and Steelers. And, of course, they’re working their way out of an 0-2 hole following losses to the Washington Football Team and the Rams.

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