Apparently, betting against the Pittsburgh Steelers in Week 1 is the best thing you can do for your wallet. 

NFL Network's David Carr said this week that the Steelers losing to the Buffalo Bills in Week 1 is the easiest game to predict. 

"The Pittsburgh Steelers are going to roll into Buffalo and get rolled out," Carr said. "The Buffalo Bills are going to be jumping. We basically just called [Josh Allen] the MVP in this show today. He's going to have a lot of fun against Pittsburgh."

The Steelers did lose to the Bills on the road in 2020, 26-15. Buffalo finished the season 13-3 and competed with the Kansas City Chiefs in the AFC Championship game. 

Many expect the Bills to carry the same success in 2021, and will start that journey in Week 1, according to Carr. 

The Steelers open as six-point underdogs to the Bills in Week 1.

More must-reads:

TODAY'S BEST
Patriots' Drake Maye starts OTAs in surprising position
Bettors are buying Bronny James hype before the 2024 NBA Draft
Mets release veteran infielder
Anderson Silva, Chael Sonnen will finish off their trilogy in a boxing ring
Victor Wembanyama, Chet Holmgren highlight 2023-24 All-Rookie team
Jaguars' Doug Pederson discusses Trevor Lawrence contract extension
Saints, star CB 'moving forward' following trade chatter
Pacers ride historic shooting performance to Game 7 blowout of Knicks
Timberwolves mount incredible second-half comeback to stun Nuggets in Game 7
Xander Schauffele proves doubters wrong with historic win at 2024 PGA Championship
Four things we learned from Joey Logano's All-Star Race win at North Wilkesboro
Phil Foden lifts Manchester City to fourth consecutive English Premier League title
Watch: Aaron Judge blasts 13th home run in Yankees' seventh straight win
Canucks won't have linchpin forward for Game 7 vs. Oilers
Jags reportedly mulling extension for Trevor Lawrence, but is that the right choice?
Gordon Hayward calls role with Thunder 'frustrating'
Mets reliever Edwin Diaz showing short shelf life of closers
Three offseason moves the 49ers must make
Watch: NASCAR drivers exchange punches after crash in All-Star Race
Knicks star offers passionate defense of HC Tom Thibodeau after Game 7 loss

Want more Steelers news?

Join the hundreds of thousands of fans who start their day with Yardbarker's Morning Bark, the best newsletter in sports.