San Francisco 49ers wide receiver Brandon Aiyuk (11). Ken Blaze-USA TODAY Sports

NFL Week 13: San Francisco 49ers vs. Philadelphia Eagles, betting picks, preview

This is likely a preview of the NFC Championship Game. If Philly wins, they are all but assured of hosting that contest, but a loss (which is expected based on the spread), really opens things up for San Francisco (and maybe Detroit or even Dallas). Philadelphia has been really good at winning ugly this season. They are capable of more but we haven't seen it. Last year's team was more dominant.  

San Francisco 49ers vs. Philadelphia Eagles Betting Trends and Odds 

Sunday, December 3, 2023 —  4:25 p.m. ET 
Odds: San Francisco -3, Over/under 48, San Francisco -162 | Philadelphia +136

This game is getting a lot of buzz because Philadelphia is not even favored, at home. For starters, San Francisco is that good and if you have been paying attention the Eagles have not been dominating. Still, it is going to be a very popular play to back the Eagles as an underdog (guilty). This is just the second time that has happened this season and the other was their outright win at Kansas City. 

Picks for San Francisco vs. Philadelphia

Philadelphia +3, Brandon Aiyuk Over 4.5 Receptions (+120)

I am willing to admit that part of this is not wanting to miss out on Philly in that underdog role. They are just so good and resilient in situations like this. Both of these teams are such tough outs because they can win in different ways. I think this is a game where Eagles QB Jalen Hurts can shine. His athleticism will help him elude a good San Francisco pass rush and create plays both running and passing. That is one element that is just not part of the game for his counterpart Brock Purdy. Both of these teams are very good and the margins are very slim. They are not quite mirror images in the how, but I trust the Philly guys to have a good game plan and am not worried about any sort of letdown after last week's emotional win over Buffalo. 

Aiyuk might be known as more of a big play guy with his average of almost 20ypc. However, this prop is right at season averages and stands out because of that payoff, +120 vs. -110. That is what we are looking for. You can't look at the last time they played due to the circumstances. 

Right now the markets are really split on this one. San Francisco is getting slightly more market interest which means that +3 will hold a little longer. I will be shocked if this line gets to +3.5. 

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