BILL INGRAM/THE PALM BEACH POST / USA TODAY NETWORK

A new generation of New England Patriots strive to stretch the franchise's recent dominance of the host Pittsburgh Steelers on Sunday afternoon.

The Patriots (0-1) have won six of the last seven meetings with the Steelers (1-0) dating back to 2013, including a 36-17 victory in the AFC Championship Game in January 2017.

However, all six of those victories came with Tom Brady under center.

Second-year quarterback Mac Jones will try to pick up where Brady left off. Jones will have to do so coming off a setback at Miami. He completed 21 of 30 passes for 213 yards with a touchdown and an interception in the Patriots' 20-7 loss to the Dolphins. He also injured his back and needed X-rays after the game, which came back negative. He was a full participant in Wednesday's practice but will be monitored throughout the week.

"I definitely feel better and yeah, I want to be able to be ready to play against Pittsburgh," Jones said. "Wasn't feeling too hot after the game, but definitely feel a lot better."

A pivotal piece of the Pittsburgh offense is also hurting. Running back Najee Harris sustained a foot injury in Week 1. Tests came back negative and he is expected to play despite being limited in practice on Wednesday.

Harris ran for just 23 yards on 10 carries in Pittsburgh's season opener against the Cincinnati Bengals, but the Steelers were still able to pull out a thrilling 23-20 win. Chris Boswell provided the late heroics, putting a 53-yard field goal between the uprights as time expired in overtime.

If Harris can't play, the Steelers would turn to undrafted rookie Jaylen Warren. Warren was solid in blitz pickup and logged three carries but totaled just seven yards, setting up this brisk assessment of his Week 1 performance from Steelers coach Mike Tomlin: "He didn't urinate down his leg and that's a great place to begin."

Much like the Patriots, somebody new directs the offense for the Steelers.

Mitchell Trubisky is in his first season with the Steelers, taking over for longtime starter Ben Roethlisberger, who had to endure New England's success against his team under Brady. Trubisky had a turnover-free debut, throwing for 194 yards and a touchdown on 21-for-38 passing against Cincinnati.

Although Sunday's meeting won't feature the Brady-Roethlisberger showdown of old, Pittsburgh head coach Mike Tomlin is still preparing for a dogfight.

"They have a mode of operation, they attack you in all three phases," Tomlin said. "They play stingy defense, they keep the point totals down, they play great at situations, they win possession downs."

The Steelers could have the upper hand if their defense plays like it did against Cincinnati. Pittsburgh intercepted Joe Burrow four times, including a pick-six, and recorded seven sacks and one fumble recovery.

Ty Montgomery, who was on the receiving end of the Patriots' only touchdown against the Dolphins, was placed on injured reserve Monday. Receiver Lil'Jordan Humphrey was elevated from the practice squad.

New England safeties Joshuah Bledsoe (groin) and Adrian Phillips (ribs) went through limited practice on Wednesday along with running back Pierre Strong Jr. (shoulder) and cornerback Shaun Wade (ankle). Linebacker Ja'Whaun Bentley (toe) did not practice.

Steelers linebacker T.J. Watt did not practice on Wednesday with a pectoral injury expected to limit him for multiple weeks. Cornerback Levi Wallace and center Mason Cole were both limited due to ankle injuries, and linebacker Rob Spillane (eye) was a full participant.

More must-reads:

TODAY'S BEST
Mavericks ride 'Luka Magic' on both ends late to win Game 1
Panthers shut out Rangers 3-0 in Eastern Conference Final opener
NBA announces 2023-24 All-NBA teams
Star Padres infielder to miss significant time with shoulder injury
LeBron James, Charles Barkley passionately defend Caitlin Clark from 'petty' haters
Roger Goodell discusses factors for possible 18-game NFL season
Cowboys QB Dak Prescott has intriguing comment on his contract situation
Celtics toying around with surprise Jayson Tatum move in conference finals
Former teammate warns Tee Higgins about pitfalls of playing on franchise tag
Watch: Timberwolves and Mavericks trade dunks in third quarter
Yankees owner Hal Steinbrenner tempers expectations for Juan Soto extension
Canucks' Rick Tocchet wins 2024 Jack Adams Award
Incredible Orioles streak finally comes to end against Cardinals
Raiders QB shares surprising reason for switching jersey number
New Jersey Devils to hire just-fired head coach to lead bench
Latest announcements show how deep Knicks' injury issues ran
Veteran WR announces retirement after nine seasons
Eagles stars defend new DC following criticism
Steelers first-round pick still confident following 'rough' practice
Angel Reese pulls notable sports ownership move

Want more NFL news?

Join the hundreds of thousands of fans who start their day with Yardbarker's Morning Bark, the best newsletter in sports.