Los Angeles Rams wide receiver Cooper Kupp. Nathan Ray Seebeck-USA TODAY Sports

The Los Angeles Rams have ruled Cooper Kupp out for their season opener against the Seattle Seahawks, and it sounds like the star wide receiver is trending toward missing multiple games.

Rams head coach Sean McVay told reporters on Friday that there is a “definite possibility” Kupp will be placed on injured reserve due to his injured hamstring.

As McVay mentioned, the Rams have until Saturday to make an IR decision with Kupp. If they do place him on IR, the soonest Kupp would be able to play is Week 5.

Kupp suffered a setback with his hamstring injury in early September. The Rams sent him to see a specialist, and McVay has said doctors are still trying to pinpoint the exact issue. None of the updates have sounded promising.

Kupp led the league with in receptions (145), receiving yards (1,947) and receiving touchdowns (16) in 2021. He was limited to nine games last season with a lingering ankle issue, recording 75 catches for 812 yards and six touchdowns. Kupp is the focal point of L.A.’s offense when healthy.

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