NASHVILLE – It looks as if the Tennessee Titans will be without wide receiver A.J. Brown as they attempt to come from behind on Sunday.

They lost their leading receiver to chest injury late in the third quarter of Sunday’s game against the Houston Texans at Nissan Stadium. Franchise officials said his return is questionable.

Brown was injured on a nine-yard reception along the Titans’ sideline with 4:09 to play in the third. He briefly received attention from the training staff before he headed to the locker room to 2:24 to go in the quarter.

Brown led the Titans with five receptions for 48 yards at the time he was hurt, and the teams trailed the Texans 19-0. As he made his way to the locker, room, however, Tennessee scored on an 18-yard Dez Fitzpatrick reception. Following a missed extra point, the Titans trailed 19-6.

The injury was Brown's second of the contest. On the second play of the game, he failed to haul in a pass from quarterback Ryan Tannehill and immediately went to the sideline because of an issue with his left hand. He came back from that one and made his first reception – a 10-yard gain for a first down – with 2:20 to play in the first quarter.

Tennessee (8-2) entered the game against Houston (1-8) without wide receiver Julio Jones, who was placed on injured reserve a week earlier.

The 2019 second-round pick out of Ole Miss entered the game as Tennessee’s leading receiver this season with 41 catches for 567 yards and three touchdowns despite the fact that he missed one full game and part of another with a hamstring injury. He also has been listed on the injury report with a knee issue in recent weeks.

Brown was particularly effective over a three-week span beginning in Week 6 when he had at least seven receptions and 91 receiving yards in victories over Buffalo, Kansas City and Indianapolis.

Brown is one of 11 players in NFL history with at least 1,000 receiving yards in each of his first two NFL seasons and was need to the Pro Bowl in 2020.

On Nov. 12, Brown revealed via social media that he has battled depression in recent years and even considered suicide during the 2020 season. Days later, he said he has learned to deal with the issues and is “in a better place mentally” these days.

More must-reads:

TODAY'S BEST
Watch: Shuttered college's baseball team's magical run ends on walk-off HR
Commanders release kicker Brandon McManus following his lawsuit
Giants ace Blake Snell's season just went from bad to worse on Sunday
Yuka Saso rallies to win her second U.S. Women's Open
Ryan Blaney's misfortune is Austin Cindric's gain after wild final lap at Gateway
Tigers to promote outfielder with stellar batting eye
Watch: Austin Cindric wins at Gateway after Ryan Blaney runs out of fuel on final lap
Report: NFL expected to reach resolution on Eagles', Falcons' tampering cases this week
White Sox's Tommy Pham voices frustrations in profane interview
Blue Jays GM has no interest in entertaining trade offers for star players
Yankees' Aaron Boone reveals rehab assignment date for ace pitcher
Dustin Poirier teases retirement following his loss to Islam Makhachev at UFC 302
Watch: Orioles slugger Gunnar Henderson clobbers 19th homer vs. Rays
11 NFL teams gain cap space from post-June 1 cuts
WNBA upgrades hard foul on Caitlin Clark to a Flagrant 1
Three takeaways as Panthers eliminate Rangers, advance to Stanley Cup Final
Corey Heim dominates at Gateway for fourth Truck Series win of 2024 season
Mets honor Darryl Strawberry in fitting fashion during number retirement ceremony
Phillies ace leaves game after taking 106 mph comebacker to hand
Real Madrid defeats Borussia Dortmund 2-0 to win Champions League