Buffalo Bills at New Orleans Saints Week 12 betting guide

The Buffalo Bills (6-4) face the New Orleans Saints (5-5) at Caesars Superdome for Week 12 of the NFL. Let's take a look at the betting lines for Thursday's matchup. The Bills started the week as 4.0-point favorites but the spread has since moved to 6.0, leaving the Bills at -256 and Saints at +205. The total points line is set at 45.0, with OVER at -110 and UNDER at -110.

• The Bills have a 5-4-1 ATS record this season, while the Saints hold a record of 5-5-0.
• The Bills have a 5-5-0 O/U record this season (meaning five games have gone over the total points line and five have gone under). The Saints have a 6-4-0 O/U record.

Points on the board

• The Bills are averaging 29.5 points per game this season (2nd in the league). Comparatively, the Saints are averaging only 25.1 (14th).
• Defensively, the Bills are giving up 17.6 points per game this season (2nd in the league), while the Saints are giving up an average of 21.8 points (10th).

Moving the chains

• With an average of 391.7, the Bills rank 5th in the league for total yards per game. Comparatively, the Saints rank 24th with just 321.3 yards per game.
• In terms of yards allowed, the Bills are giving up 283.7 per game this season (1st in the league), while the Saints are giving up an average of 342.0 (10th).

Ascendency in the air

• The Bills have recorded 272.9 passing yards per game this season (7th in the league). Comparatively, the Saints' defense has given up 252.2 passing yards per game (22nd).
• Meanwhile, the Saints have recorded 203.4 passing yards per game this season (26th in the league), while the Bills' defense has given up 181.8 passing yards per game (2nd).

Advantage on the ground

• Looking at the ground game, the Bills have recorded 118.8 rushing yards per game this season (12th in the league). Conversely, the Saints are giving up 89.8 rushing yards per game (3rd).
• On the other hand, the Saints have recorded 117.9 rushing yards per game this season (13th in the league), while the Bills are giving up 101.9 rushing yards per game (9th).

Protecting the ball

• Looking at their ability to force turnovers, the Bills have recorded 24 total takeaways this season (2nd in the league), while the Saints have failed to perform at the same level, recording 14 (T12th).
• On offense, the Bills have recorded 14 total giveaways this season (T17th in the league), while the Saints have taken better care of the ball, recording 11 (T7th).

First to Score

The Bills are -145 to score first, while the Saints are +115.

• The Bills have scored first in seven of their 10 games this season.
• The Saints have scored first in two of their 10 games this season.

Which team will score the first touchdown?

• The Bills have recorded the first touchdown in seven of their 10 games this season.
• The Saints have recorded the first touchdown in four of their 10 games this season.

First Scoring Play

Buffalo Touchdown                 4 / 10   +150

Buffalo Field Goal                   3 / 10   +350

Buffalo Safety                         0 / 10   +9000

New Orleans Touchdown       1 / 10   +340

New Orleans Field Goal         1 / 10   +300

New Orleans Safety               0 / 10   +8000

Which team will get a quick start?

The Bills are -190 to be the first team to reach 10 points, while the Saints are +155.

• The Bills have been the first to score 10 points in seven of their 10 games this season.
• The Saints have been the first to score 10 points in five of their 10 games this season.

First Quarter Moneyline

The Bills are favored in the 1st Quarter Moneyline market, currently at -165, while the Saints are +145.

• The Bills have a 8-1-1 first quarter W/L/T record this season, while the Saints hold a record of 3-5-2.

Last Time They Met

The Saints recorded a 47-10 beatdown over the Bills at Highmark Stadium when these teams last met in Week 10, 2017. Mark Ingram II shredded the Bills' defense on that day, recording 131 rushing yards and 3 rushing TDs.