The United States' John Isner withdrew from the U.S. Open on Wednesday after fracturing his left wrist during his first-round win over Federico Delbonis of Argentina.
Isner sustained the injury after a fall, he tweeted.
He was scheduled to play No. 28 seed Holger Rune of Denmark on Thursday, but with his premature exit, Rune will advance to the third round of the tournament on a walkover.
Isner, 37, is currently ranked 48th in the world. He won the Miami Open back in 2018 and has also finished as runner-up in four Masters 1000 finals events. His best Grand Slam result was a semifinal finish at Wimbledon in 2018.
He is best known for winning the longest pro tennis match ever, a 6-4, 3-6, 6-7 (7), 7-6 (3), 70-68 victory over France's Nicolas Mahut in the first round at Wimbledon in 2010. The match stretched over three days and lasted 11 hours, 5 minutes.
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