Brad Penner-USA TODAY Sports

Adrian Sampson outdueled two-time National League Cy Young Award winner Jacob deGrom on Tuesday night, tossing six scoreless innings to lead the visiting Cubs past the Mets 4-1.

It was the Cubs' second win in as many nights over the Mets (89-54), who entered Tuesday 1 1/2 games ahead of the Braves in the National League East. The Braves played the Giants later Tuesday night.

deGrom (5-2) allowed three runs on four hits and no walks while striking out 10 in six innings. It was the third time he had struck out at least 10 in eight starts this season and the 56th double-digit strikeout effort of his career.

Ian Happ homered in the second off deGrom for the Cubs (60-82), who used small ball to produce two more runs against the Mets' ace in the fourth, when Franmil Reyes singled and scored on a sacrifice fly by Yan Gomes and Happ scored on a safety squeeze by Patrick Wisdom.

David Bote added a solo homer in the seventh for Chicago.

Sampson (2-6) allowed two hits, walked four and struck out three in his longest scoreless outing as a big-leaguer. Michael Rucker tossed 1 1/3 one-hit innings and Brandon Hughes gave up one hit -- Pete Alonso's one-out homer in the ninth -- while recording the final five outs.

The Mets missed their best chance to score against Sampson in the first. Brandon Nimmo drew a leadoff walk and Francisco Lindor flew out before Nimmo was erased when he was hit in the foot by Jeff McNeil's grounder in between first and second.

Alonso then hit a towering fly ball to left field that landed centimeters to the left of the foul pole. Alonso, who completed his home run trot while manager Buck Showalter trotted onto the field to request a review, drew a walk on the next pitch and spiked his bat, leading to a brief verbal exchange with Sampson. The Cubs' right-hander escaped the jam by getting Daniel Vogelbach to hit a comebacker.

The Mets got just one more runner into scoring position before Alonso's blast in the ninth.

Jeff McNeil had two hits for the Mets.

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