The Buffalo Bills presumably aren't too disappointed over how their 2022 schedule has shaped up. Troy Babbitt-USA TODAY Sports

Bills to be most 'rested' team of 2022 NFL regular season?

It was learned before Thursday night's full NFL schedule release that the Buffalo Bills will begin their pursuit of a trip to Super Bowl LVII at the defending-champion Los Angeles Rams on the opening night of the 2022 season that will be celebrated on Sept. 8. 

Even if the Bills go on to lose that contest, it could ultimately prove to be a positive for the perceived championship contender. 

As Michael David Smith of Pro Football Talk shared, the Bills are on track to have the highest "rest differential" among clubs for the upcoming campaign. Throughout the season, Buffalo will be more rested than opponents by a total of 13 days.

For example, the Bills will have extra time after Week 1 to prepare for the Week 2 home game against the Tennessee Titans that is set to occur in prime-time on Monday, Sept. 19. Later in the year, Buffalo will be on its bye in Week 7 before it hosts the Green Bay Packers on Oct. 30. The Packers play at the Washington Commanders on Oct. 23.

Following last month's NFL Draft, sportsbooks listed the Bills as the overall betting favorites to win the Super Bowl in February. Coming off Thursday's made-for-television event, FanDuel has Buffalo at +650 to be the last team standing. The Tampa Bay Buccaneers are second at +750. 

The Bills may start things off at 0-1 in September, but they theoretically should be feeling alright, physically speaking, in early January. 

More must-reads:

TODAY'S BEST
Ant-Man leads Timberwolves to Game 1 upset of Nuggets
Luis Arraez makes history in Padres debut
Corey Heim dominates Truck Series race at Kansas Speedway while tempers flare on pit road
Lionel Messi sets MLS record with monster game
Watch: Anthony Edwards does it all for Minnesota
Watch: 150th Kentucky Derby ends in three-horse photo finish
Clippers could see nine-time All-Star jump ship this summer
Phillies get rough injury news on Trea Turner
Watch: Yankees star Aaron Judge receives first career ejection after arguing called third strike
Mavericks lose key player for 'significant period of time'
Blue Jays manager John Schneider blasts team after latest loss
Lakers make another big change after firing Darvin Ham
Draymond Green doubles down on Knicks' inability to win a championship
Phillies lose two-time All-Star to injured list
NBA announces punishment for Lakers star over actions in elimination game
Heat may be cooling on Jimmy Butler's long-term future
NFL insider defends former Steelers QB Kenny Pickett from 'bust' label
Nuggets may miss this player as postseason run continues
Report: Russell Westbrook situation 'far more challenging' than previously thought
Kansas City Chiefs release former second-round pick at WR

Want more sports news?

Join the hundreds of thousands of fans who start their day with Yardbarker's Morning Bark, the best newsletter in sports.