Baltimore Ravens linebacker Justin Houston Mark J. Rebilas-USA TODAY Sports

The Ravens look set to be without several key defenders against the Lions on Sunday. They placed three defensive starters on their reserve/COVID-19 list Friday.

Outside linebackers Justin Houston and Jaylon Ferguson join defensive linemen Brandon Williams and Justin Madubuike on Baltimore’s coronavirus list. While differing protocols exist for vaccinated an unvaccinated players, Friday placements on the virus list leave teams in a bind. This quartet is set to miss Baltimore’s Week 3 game.

This continues a brutal season for the Ravens on the availability front. Baltimore is already without defensive end Derek Wolfe, having ruled out the veteran lineman due to a back injury. Williams has been a starter since 2014, while Madubuike played 49% of the team’s defensive snaps in Week 2.

Houston, 32, has started both Baltimore’s games, lining up opposite Tyus Bowser. The Ravens do have first-round pick Odafe Oweh and Bowser set to be available. Pernell McPhee's status is uncertain due to a shoulder injury. Houston, who managed to avoid injuries during both his Colts seasons, will miss his first game since the 2018 season. The veteran edge rusher does not have a sack yet this season but obviously serves as a key player for a Ravens team that let Matt Judon and Yannick Ngakoue walk in free agency.

Baltimore withstood its numerous injuries to upend Kansas City on Sunday night, but the AFC power’s lineup will be filled with backups in Detroit. The team will again be without left tackle Ronnie Stanley on Sunday as well, ruling the All-Pro blocker out due to an ankle injury.

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