New England Patriots offensive tackle Isaiah Wynn Sam Navarro-USA TODAY Sports

Patriots OL Isaiah Wynn ruled out vs. Bills

Saturday night's NFL playoff slate pits the AFC East-champion Buffalo Bills against their division rivals, the New England Patriots. It will be the third and most important meeting between the clubs this season with a trip to the AFC divisional round on the line.

The Patriots will be without starting offensive lineman Isaiah Wynn.

The team's first-round draft choice from 2018 is dealing with a hip ailment and was listed as questionable on the New England injury report entering the week.

Wynn played in 16 of the team's 17 games this season and was on the field for 100% of the Patriots' offensive snaps in 10 separate contests, including both battles against Buffalo. New England won the first meeting with the division foe in Week 13 by a 14-10 final but lost 33-21 in Week 15.

The Bills and Patriots kick off at 8:15 p.m. ET on Saturday.

More must-reads:

TODAY'S BEST
Why the Wizards made the right hiring with HC Brian Keefe
Oilers rally from early deficit to beat Stars, tie WCF
Another masterpiece by Paul Skenes caps remarkable calendar year for rookie phenom
Bengals HC Zac Taylor addresses holdouts from pair of star receivers
Scott Boras makes telling comments on future of Yankees' Juan Soto
Star Arizona guard makes huge decision on NBA Draft status
Iga Swiatek, Naomi Osaka have opposite reactions to crowd following epic French Open match
Kyrie Irving praises Karl-Anthony Towns for overcoming 'unfair criticism' in Game 4
Watch: Minnesota wins inaugural PWHL Walter Cup
Mets outfielder reveals details of team meeting following latest lopsided loss
Mavericks provide notable status update on star rookie ahead of Game 5
Watch: Benches clear after Giants buzz Bryce Harper
Wizards make decision on their new head coach
Veteran sportscaster gives valuable insight into Caitlin Clark's WNBA debut
Patriots QB Jacoby Brissett addresses 'elephant in the room'
AEW owner stays quiet on potential interest in top WWE star
Donovan Mitchell's influence on Cavaliers listed among 'most powerful' in the NBA
Clippers 'determined' to keep these two star free agents
AEW sustains another major injury blow after Double or Nothing
Celtics HC Joe Mazzulla offers update on Kristaps Porzingis ahead of NBA Finals

Want more sports news?

Join the hundreds of thousands of fans who start their day with Yardbarker's Morning Bark, the best newsletter in sports.