Sunday Six-Pack: NFL Week 13 betting guide

Then there's the Arizona Cardinals, allowing the second-most yards per game to running backs and the second-most touchdowns per game. Harris has four touchdowns this year and had a big day last week in the first game since OC Matt Canada was fired.

These two should pile up the yards and seem like a great bet to find the end zone.

Bounce-back coming: Detroit -4

The Detroit Lions are off a very disappointing home loss against the Packers on Thanksgiving, but with some extra rest, they should get back on track against a mediocre New Orleans team.

The Saints are dealing with some injuries to their pass-catchers which might limit their ability to move the football.

The Lions are 7-4 ATS this season and just the better team here.

Let the rookie rumble: Bijan Robinson over 59.5 rushing yards (-110 ESPN)

The New York Jets have allowed the fifth-most yards per game to running backs this year, and no team sees a higher percentage of runs against them than the Jets. 

That matches up well with an Atlanta Falcons team that loves to run, and it particularly makes things look inviting for rookie RB Bijan Robinson. Robinson is ramping up of late, seeing 38 carries over the past two games, both of which ended with 90+ rushing yards.

Robinson is over this line in three of his last four and six of the past seven RBs to see New York have gone over.

Happy with Zappe: Bailey Zappe over 201.5 passing yards (-114 FanDuel)

Come on, let's take a chance on Bailey Zappe here, set to make the start at QB for the New England Patriots. Zappe gets an ideal opponent to build up some production against in the Los Angeles Chargers.

The Chargers have allowed the most passing yards per game, the second-most pass attempts, the eighth-highest completion rate and the third-highest yards per pass attempt.

That all should benefit Zappe here, and this is one of the lower lines you'll ever see for the passing yard total. 10 of the 11 QBs to see Los Angeles have gone over their yardage total.

Michael the Machine: Michael Pittman Jr. over 6.5 receptions (-115 DraftKings)

Michael Pittman Jr. is on a tear for the Indianapolis Colts, catching 8+ balls in four straight games and five of his last six. That volume should continue here against a Titans team allowing the fourth-most receptions per game to WRs.

Pittman has averaged 10.1 targets per game this season.

The disrespect!: Eagles +3

We don't hate Philly on the moneyline here at all. We're blown away the 10-1 Eagles are home 'dogs to San Francisco this Sunday.

This is the biggest game of the weekend, and we're liking the team that just keeps winning against quality opponents, especially at home. They have the advantages in the trenches, which could and should be the difference here. Even if they don't win, we'll grab the points happily.