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The Louisville Cardinals traveled up to South Bend and defeated the Fighting Irish, 75-60, to improve to 13-3 in ACC play. Louisville had 16 assists on 24 made field goals and shot 49.1% in the game. Chucky Hepburn scored a team-high 16 points to go with six assists, three steals, and two rebounds. Terrence Edwards Jr. had 14 points, three rebounds, two assists, and two steals. Ryene Smith hit four three-pointers to account for his 12 points. Markus Burton had 22 points for Notre Dame on 8-18 shooting with four assists and three rebounds.

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