Watch: No. 16 Fairleigh Dickinson makes huge plays late to slay No. 1 Purdue

Moore added to his unbelievable night when he got airborne for an incredible block with 12.5 seconds remaining to prevent Purdue from cutting into the five-point deficit.

The Knights are just the second 16-seed to win an NCAA Tournament game. UMBC was the first 16-seed to win a tournament game when it defeated Virginia 74-54 in 2018.

As FDU closed in on its upset win, UMBC's social media account chimed in with tweets supporting their fellow underdog in pursuit of a historic upset.

It's hard to overstate just how huge of an upset the Knights' win was. They went 4-22 a season ago and needed a win in a First Four game against Texas Southern to advance to the round of 64. As ESPN Stats & Info noted, Fairleigh Dickinson is the first team from the Northeast Conference to advance to the round of 32.

Per Sports-Reference, the win was also the biggest upset by pregame point spread in tournament history. As Heat Check CBB noted on Twitter, Purdue was a 23.5-point against Fairleigh Dickinson, 2.5 points more than Missouri was favored by in 2012 against Norfolk State.

Questions will abound for Purdue as to why the likely National Player of the Year Zach Edey was a nonfactor late in the game. The massive 7-foot, 4-inch, 285-pound Edey had 21 points and 15 rebounds but didn't attempt a field goal after he tied the game at 49 with a two-point bucket with 9:25 remaining.

The aftershock of Fairleigh Dickinson's win will likely reverberate for quite some time. That's what happens when a giant hits the ground.