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Missouri vs. Oklahoma odds: Opening point spread released
(6) fumbles the ball during the second half against the Missouri Tigers at Faurot Field at Memorial Stadium. Mandatory Credit: Jay Biggerstaff-Imagn Images

Missouri travels to Oklahoma for a Week 13 clash in the Southeastern Conference. With game day approaching, the opening odds and point spread have been revealed.

The Sooners have opened as 9.5-point favorites over the Tigers. The over/under is set at 42.5 points. All odds are courtesy of BetMGM.

How to watch Missouri at Oklahoma

Time: Noon ET
Channel: TBD/Fubo TV (Streaming)
Location: Norman, OK

This game will be a matchup between two former Big 12 rivals, so there’s a rich history between the Tigers and Sooners. The series was renewed for the first time since 2011 during the 2024 season — OU’s first in the SEC.

Missouri would defeat Oklahoma in Columbia 30-23 last season, but the all-time series heavily favors the Sooners. Oklahoma leads the all-time series 67-25-5 dating back to 1902.

Before the Tigers left the Big 12, Oklahoma won eight of the last nine meetings between the two teams. Not all meetings have come during the regular season, however. Missouri and Oklahoma met in back to back conference championship games in 2008 and 2009.

The last time Missouri beat Oklahoma as a member of the Big 12 came during the 2010 season when Blaine Gabbert and the No. 18 Tigers upset the top-ranked (BCS) Sooners 36-27. Fans stormed the field in celebration and tore down both goal posts in the aftermath. At least one made its way to a local tavern following the upset victory.

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This article first appeared on 5 GOATs and was syndicated with permission.

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