Ohio State Buckeyes wide receiver Jeremiah Smith (4) catches a pass Samantha Madar/Columbus Dispatch / USA TODAY NETWORK via Imagn Images

Opening Spread Released for Purdue vs. No. 1 Ohio State in Week 11

Originally posted on Purdue Boilermakers on SI
By Dustin Schutte | Last updated Nov 2, 2025 7:50 AM ET

Top-ranked Ohio State has opened as a massive favorite for the Week 11 clash against Purdue. The Buckeyes are entering Saturday's game with an undefeated 8-0 record, while the Boilermakers sit at 2-7 and are still searching for their first Big Ten win of the season.

Per FanDuel Sportsbook, Ohio State has opened as a 28.5-point favorite for Saturday's game. It is the largest point spread Purdue has faced this season — although the Boilers have been 20-point underdogs multiple times in 2025.

Ohio State is coming off a 38-14 win over Penn State in Columbus over the weekend. Purdue had its chances to pull off an upset against No. 21 Michigan, but ultimately the Boilers fell 21-16 in Ann Arbor.

Saturday's game between the Buckeyes and Boilermakers marks the third straight season in which the two teams have played. Ohio State posted convincing victories in 2023 and 2024. Ryan Day also led OSU to a win over Purdue in 2021.

Kickoff between Purdue and Ohio State is scheduled for 1 p.m. ET and the game will air on Big Ten Network.

Purdue's success vs. Ohio State at Ross-Ade Stadium

Although Ohio State has won three straight games against Purdue, the Boilermakers have had success against the Buckeyes in West Lafayette. Could we see another massive upset at Ross-Ade Stadium this weekend?

Since 2000, Purdue has defeated Ohio State five times, all of those wins coming in West Lafayette. The most recent was a 49-20 victory on Oct. 20, 2018. The Boilermakers also posted wins over the Buckeyes in 2000, 2004, 2009, and 2011.

Ohio State head coach Ryan Day has had no trouble with the Boilermakers during his time in Columbus, though. The two teams have played three times since Day took over, with the Buckeyes securing convicing wins each time.

The Buckeyes won a 59-31 shootout in Columbus in 2021, clobbered Purdue 41-7 in West Lafayette in 2023 and pitched a 45-0 shutout in The Horseshoe last season. Day's average margin of victory against the Boilers is 39 points per game.