So far in the Brent Brennan era of Arizona football, the Wildcats have had their struggles on the road with four-straight losses dating back to last year. UA has lost those games by an average of 28 points and have fallen behind by double-digits in all four games.
On Saturday, Arizona (4-3, 1-3) were able to get things going early by striking quickly as quarterback Noah Fifita hit receiver Tre Spivey for a 70-yard touchdown pass, which seemed to set the tone early for the offense.
Despite the fast start, Arizona found itself trailing 21-14 to Houston (6-1-,3-1) at the half thanks to defensive struggles in the second quarter. And once again, the Wildcats lost the middle eight of the game, which resulted in a Cougars 31-28 win over the Wildcats.
Similarly to the BYU game, Arizona’s defense struggled against the run as Houston quarterback Conner Weigman sliced and diced the middle of the defense by racking 98 yards on 14 carries. Meanwhile as a team, the Cougars rushed for 232 yards for the game.
The rushing attack for Houston really opened things up in the secondary against Arizona as the Cougars totaled 164 yards through the air and racked up three passing touchdowns.
Just two weeks ago, the Wildcats’ defense hadn’t given up a passing touchdown all season. Now, Arizona has allowed four in two games.
Near the start of the fourth quarter, Arizona was able to cut into the lead with a rushing score from Spivey, which sparked the offense.
After getting a key stop with a missed 48-yard field goal by Houston, Arizona’s offense methodically moved the ball down field and tied the game up on a rushing touchdown from running back Kedrick Reescano.
Although the Wildcats battled back in the fourth quarter to tie the game, Houston got the ball back with under five minutes left and relied on its running game to set up the game-winning 41-yard field goal against Arizona.
It wasn’t just Weigman that gashed the Wildcats’ defense on the ground, Houston running back Dean Connors racked up 100 yards on 20 carries and really seemed to wear down Danny Gonzales’ defense.
SANCHEZ THROUGH THE POST FOR THE DUB @e10_sanchez pic.twitter.com/p8mqLjctqa
— Houston Football (@UHCougarFB) October 18, 2025
Arizona gave itself a chance to come up with a late-game stop to get the ball back to the offense, but failed to roundup Weigman, who converted a 3rd and 2 situation.
At the end of the day, it was another heartbreaking loss for an Arizona team that seemed to be haunted by road games with the losing streak growing to five games for Brennan and his staff.
Now that the game is in the books, we at Arizona Wildcats On SI have put together our three observations from the Arizona-Houston game.
— Houston Football (@UHCougarFB) October 18, 2025
To the house @tannerkoziol88 pic.twitter.com/hjYdvOTwET
— Houston Football (@UHCougarFB) October 18, 2025
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