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As it turns out, the Louisville baseball program will not have one of their best players at their disposal to start the season.

Preseason All-American outfielder Zion Rose is set to miss the season opening series vs. Michigan State due to an ankle injury, head coach Dan McDonnell said in a radio interview with 93.9 The Ville on Thursday.

The 6-foot-1, 200-pound left fielder is coming off of a great sophomore season for the Cardinals. Starting all 66 games in 2025, he hit .310/.396/.552 with a career-best 13 homers and a team-best 67 RBI. He also finished with 16 doubles, three triples, 31 walks and 31 stolen bases.

Rose played a key role in helping Louisville go 42-24 overall, culminating in the program's sixth College World Series appearance. Not only did he earned First-Team All-ACC honors last season, he was tabbed as a Second-Team Preseason All-American and named to the Golden Spikes Award Preseason Watch List ahead of the current season.

The Chicago native burst onto the scene as a true freshman in 2024. In 166 at-bats across 44 games and 43 starts, Rose posted a team-best .380 batting average, while also collecting five home runs and 32 RBI. He also tallied nine doubles, a whopping five triples, 19 walks and 10 stolen bases.

He also excelled during conference play that season. In 28 ACC games, he hit .396 - the second-most of any player in the league - along with a pair of homers and 17 RBI. Rose led Louisville in conference play in average, hits, runs, triples and on-base percentage.

Picked in the preseason to finish fourth in the ACC and ranked as high as No. 8, Louisville will start year 20 under head coach Dan McDonnell with a home series against Michigan State. First pitch of game one is set for Friday, Feb. 13 at 3:00 p.m. EST,

This article first appeared on Louisville Cardinals on SI and was syndicated with permission.

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