Watch: Louisville RB Isaac Brown | 2025 Players To Watch

Louisville running back Isaac Brown emerged on the scene for the Cardinals in 2024 and established himself as one of the best freshmen in all of college football. He was named ACC Offensive Rookie of The Year in addition to being the ACC Rookie of The Year after rushing for 1,173 yards and racking up 12 all-purpose scores. Brown led all Power Four conference runners at an amazing 7.2 yards per rush. His efforts garnered him second-team All-ACC honors as he was the first freshman running back in UL history to rush for 1,000 yards in addition to setting the new freshman record. Brown's dynamic ability at 5'9" and 190 pounds spread to all parts of the field as he accumulated 1,527 all-purpose yards.