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Practice and qualifying are in the books, the starting grid is set, and Indy 500 odds are open for betting ahead of Sunday's 108th running of the "The Greatest Spectacle in Racing."
Team Penske's trio of Scott McLaughlin, Will Power and Josef Newgarden qualified first, second and third, respectively, for the Indy 500 and are therefore atop the odds board.
Perhaps a bit more surprising is NASCAR's Kyle Larson, who is attempting to complete "the double," which is racing in the Indy 500 (12:30 p.m. ET, NBC) and Coca-Cola 600 (6 p.m. ET, FOX) in the same day, sitting among the favorites as well.
While nobody questions Larson's talent, the 2021 NASCAR Cup Series champion was blazing fast in qualifying, putting his No. 17 Arrow McLaren Chevy fifth on the starting grid. He heads into Sunday with +650 Indy 500 odds.
Below is a rundown of the latest Indy 500 odds, as well as what prices looked like back on May 13 before cars hit the track at Indianapolis.
Indy 500 Odds
| Driver | May 13 | May 25 |
|---|---|---|
| Scott McLaughlin | +1200 | +500 |
| Josef Newgarden | +900 | +550 |
| Will Power | +1200 | +650 |
| Kyle Larson | +650 | +700 |
| Alexander Rossi | +1600 | +1000 |
| Colton Herta | +2000 | +1000 |
| Pato O'Ward | +700 | +1100 |
| Alex Palou | +400 | +1200 |
| Scott Dixon | +1000 | +1600 |
| Rinus Veekay | +2200 | +2000 |
| Santino Ferrucci | +2000 | +2000 |
| Helio Castroneves | +4000 | +2000 |
| Kyle Kirkwood | +2000 | +2800 |
| Felix Rosenqvist | +1800 | +3000 |
| Takuma Sato | +3000 | +3000 |
| Ryan Hunter-Reay | +7000 | +4000 |
| Ed Carpenter | +5000 | +6000 |
| Marco Andretti | +6000 | +6000 |
| Christian Rasmussen | +20000 | +6000 |
| Callum Ilott | +4000 | +7000 |
| Marcus Ericsson | +1500 | +7000 |
| Marcus Armstrong | +5000 | +8000 |
| Kyffin Simpson | +20000 | +8000 |
| Linus Lundqvist | +2500 | +8000 |
| Christian Lundgaard | +4000 | +8000 |
| Conor Daly | +3500 | +10000 |
| Graham Rahal | +4000 | +10000 |
| Agustin Canapino | +20000 | +10000 |
| Romain Grosjean | +6000 | +10000 |
| Sting Ray Robb | +20000 | +20000 |
| Tom Blomqvist | +15000 | +20000 |
| Pietro Fittipaldi | +10000 | +25000 |
| Katherine Legge | +30000 | +50000 |
The Team Penske trio of McLaughlin, Newgarden and Power are the three most likely drivers to win based on live Indy 500 odds, with NASCAR's Larson just behind at +700.
Larson's Arrow McLaren teammate, Alexander Rossi, rounds out the top five with +1000 odds to win the Indy 500.
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