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Top MLB DFS Start‘em/Sit‘em For May 23rd
- Mar 2, 2025; Scottsdale, Arizona, USA; San Francisco Giants first base Wilmer Flores (41) fields a throw to force out Los Angeles Angels shortstop Tim Anderson (77) at first base during the third inning at Scottsdale Stadium. Mandatory Credit: Joe Camporeale-Imagn Images

The week is officially ending, and Friday’s top MLB DFS lineups could help players win cash prizes to end the week with a bang. Friday’s 16-game slate will end the week with a bang for fantasy players. With the weekend here, DFS players could start it in style and win cash prizes.

Friday’s games will keep the week on a hot streak with the Boston Red Sox and the Baltimore Orioles. Another game that fantasy players should have players in tonight’s top MLB DFS lineups should be the Milwaukee Brewers and the Pittsburgh Pirates.

Another week of May is ending, and fantasy players could win cash prizes by using the top MLB DFS lineups for the week.

May 23rd Top MLB DFS Lineup Starters

C Logan O’Hoppe, Miami Marlins at Los Angeles Angels ($3,900 – DraftKings/3,100-Fanduel)

To start Friday night’s top MLB DFS lineups, Logan O’Hoppe of the Los Angeles Angels should be in your lineups. During a dominating win against the Athletics, O’Hoppe went 2-5 with a home run and two strikeouts.

O’Hoppe has been one of the Angels’ bright spots in another down year, and could have another great game against the Marlins. Fantasy players could see O’Hoppe have another home run against a weak Marlins pitching staff.

1B Vladimir Guerrero Jr, Toronto Blue Jays at Tampa Bay Rays ($4,900 – DraftKings/3,200-Fanduel)

Vladimir Guerrero Jr of the Toronto Blue Jays should be in their lineups for Friday’s top MLB DFS lineups. In the win against the Padres, Guerrero Jr went 0-5 with a run and a strikeout.

Vlad Jr has been playing well for the Blue Jays this season, with three hits in his last five games. DFS players could see a multi-hit game from the Jays slugger against the Rays tonight in Tampa.

3B Eugenio Suarez, Arizona Diamondbacks at St. Louis Cardinals ($4,200 – DraftKings/3,400-Fanduel)

The last player to have for your fantasy lineups is Eugenio Suarez of the Arizona Diamondbacks in tonight’s DFS lineups. In a loss against the Dodgers, Suarez went 2-4 during a brutal loss against a divisional rival.

Suarez has been a top slugger for the Diamondbacks this season and could have another great game tonight. DFS players could see Suarez have a home run against the Cardinals tonight in St. Louis.

May 23rd Top MLB DFS Benchwarmers

Mar 31, 2025; West Sacramento, California, USA; Athletics shortstop Jacob Wilson hits an RBI ground out during the fourth inning against the Chicago Cubs at Sutter Health Park. Mandatory Credit: Sergio Estrada-Imagn Images

SS Jacob Wilson, Philadelphia Phillies at Athletics (4,300 – DraftKings/3,000-Fanduel)

Jacob Wilson is the first player who should be on your top MLB DFS fantasy benches for this Friday night. In the loss against the Angels, Wilson went 2-5 with a run for the A’s yesterday.

The Athletics have been on a cold streak heading into the weekend, and Wilson could have a weak game tonight. DFS players could see Wilson struggle with a hitless game against the Phillies’ pitching staff tonight.

OF Cedric Mullins, Baltimore Orioles at Boston Red Sox ($4,300 – DraftKings/3,400-Fanduel)

Cedric Mullins of the Baltimore Orioles is another player who should be on your fantasy benches tonight for DFS lineups. In the win against the Brewers on Wednesday, Mullins went 2-4 with an RBI in the extra-innings win.

The Orioles are having a nightmare season, and after the postponement of yesterday’s game, Mullins could have a weak game. DFS players could see Mullins have a multi-strikeout game against the Red Sox tonight.

2B Luisangel Acuna, Los Angeles Dodgers at New York Mets ($3,600 – DraftKings/2,500-Fanduel)

Luisangel Acuna, of the New York Mets, should be the last player on your top MLB DFS bench for the night. In the win against the Red Sox on Wednesday, Acuna went 2-4 with a run in the win against Boston.

 Acuna has been playing well, but has been getting cold after a hot start to the season. DFS players could see a multi-strikeout game from Acuna against a strong Dodgers pitching staff tonight.

Total Apex Media Stack Of The Day

Friday’s top MLB DFS stack should be the Los Angeles Angels, Taylor Ward, Zach Neto, and Jorge Soler. The Angels have been playing their best baseball in May, and could have another great game tonight. Fantasy players should take a chance with the Angels against a weak Marlins team tonight. 

In yesterday’s win against the Athletics, Ward had a grand slam and could have another solid game against the Marlins. Ward has been playing well for the Angels this season and could have another solid game for the Halos. DFS players could see Ward have another home run against the Marlins and win cash prizes in DFS lineup games tonight.

Another player who could play well for tonight’s top MLB DFS lineup is Neto, who has been playing great tonight. In yesterday’s win, Neto went 3-5 with an RBI during the blowout against the Athletics. DFS players could see Neto have another multi-hit game for the Angels, and fantasy players could help people win cash prizes.

The last player to have in tonight’s top MLB DFS lineup stack is Soler and his incredible power. In the win against the Athletics, Soler went 1-4 with a walk, a run, and a strikeout. Soler has been hitting well for the Angels this season and could have another good game tonight. Fantasy players could see Soler have a home run against the Marlins, and win cash prizes to start the weekend for DFS players. Tonight could be a great start to the weekend for the top MLB DFS lineups.

This article first appeared on Total Apex Fantasy Sports and was syndicated with permission.

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