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- May 7, 2025; Tampa, Florida, USA; Philadelphia Phillies shortstop Trea Turner (7) reacts withdesignated hitter Kyle Schwarber (12) after hitting a home run against the Tampa Bay Rays in the third inning at George M. Steinbrenner Field. Mandatory Credit: Nathan Ray Seebeck-Imagn Images

MLB Parlay Picks For July 21, 2025

Originally posted on Total Apex Fantasy Sports
By Shawn Pettinati | Last updated Jul 21, 2025 11:36 AM ET

The hot streak continues as we hit on another MLB parlay, making that five since June 28. Our season record now sits at 47-32 ATS. Our followers know we target games, seeing respected money and, more precisely, reverse line movements. We have another three selections on tap for you, along with some additional leans that we like based on the line movement. The betting lines discussed are the consensus at Vegas Insider and are subject to change.

MLB Parlay Leg #1: Washington Nationals ML +108

Leading off today’s MLB parlay is the Washington Nationals over the Cincinnati Reds. We spot our first reverse line movement on the day in this tilt. The Nationals are seeing just 22% of the money, and the line continues to move in their direction. Washington opened up as a +137 underdog and now sits at +108. They are 4-1 SU in their last five versus the Reds and 7-3 in the last 10. Pair that with the fact that they are 7-3 in the last 10 as an underdog against the Reds. We continue are consistent trend of siding with the sharps here and take the Nationals for play number one!

MLB Parlay Leg #2: Philadelphia Phillies Alternate TT over 3.2 -215

Our second leg brings us to the Philadelphia Phillies alternate team total over 3.5 runs. The Phils are the second biggest chalk on today’s MLB betting slate and are scheduled to face Boston’s Walker Buehler. Buehler brings a hefty 6.12 ERA into tonight’s interleague match-up and has yielded 22 earned runs over his last 22.1 innings pitched. In addition, on their current homestand, the Phillies are averaging over five runs per game. We continue to target the team total of the big betting favorites. Phillies alternate team total over 3.5 runs for play number two!

MLB Parlay Leg #3: San Francisco Giants ML +106

Apr 4, 2025; San Francisco, California, USA; San Francisco Giants third base Matt Chapman (26) rounds the bases after hitting a home run during the sixth inning against the Seattle Mariners at Oracle Park. Mandatory Credit: Bob Kupbens-Imagn Images

Closing out today’s MLB parlay is the San Francisco Giants over the Atlanta Braves. The sharps on the Giants this evening as well, as the respected money has driven the opening +137 number down to +106. Atlanta lost their last two games to the Yankees over the weekend, yielding 16 runs, and is just 4-6 SU in their last 10 games overall. They have also lost four of their last five games at home. The Giants have won three straight and four of five against Atlanta. We back the sharps again in this one, Giants on the money line for play number three!

Additional Leans: Angels ML, Rays TT over 4.5, Athletics ML, Astros ML, Twins ML

Final Thoughts

The beauty of our MLB parlays is that we can provide our followers with three individual plays. We will play these picks SU because the hit rate on a three-team parlay is about 6-1, not a long-term profitable betting strategy. Hitting on the parlay is simply icing on the cake. We avoid public plays, which tend to be the betting favorites. Please follow us on X and Facebook as the MLB season continues toward the Fall Classic. Let’s keep the hot streak going and get you another three winners. And remember: Follow or Fade!