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Top MLB DFS Start‘em/Sit‘em For September 24th
- Aug 8, 2025; San Diego, California, USA; Boston Red Sox right fielder Wilyer Abreu (52), left, Roman Anthony (19), center, and Jarren Duran (16) celebrate after the Red Sox beat the San Diego Padres at Petco Park. Mandatory Credit: Denis Poroy-Imagn Images

With the last week of the MLB season heating up, fantasy players can win cash prizes in tonight’s top MLB DFS lineups. Wednesday’s 15-game slate will keep the week going with a strong slate of games for fantasy lineups. The postseason will start next week, and fantasy players could win cash prizes in tonight’s top MLB DFS lineups and fantasy stacks.

Wednesday’s games will keep the week going in style, with the Boston Red Sox traveling to Toronto to face the Blue Jays with playoff implications for both teams. Fantasy players for tonight’s slate of games could also win cash prizes with the St. Louis Cardinals facing off against the San Francisco Giants in a West Coast showdown for a wild-card spot. 

The season is ending soon, and fantasy players could win cash prizes with this midweek slate of games for tonight’s top MLB DFS lineups and fantasy stacks. 

September 24th Top MLB DFS Lineup Starters 

SS Trevor Story, Boston Red Sox at Toronto Blue Jays ($4,600 – DraftKings/3,700-Fanduel)

To start Wednesday night’s top MLB DFS lineups, Trevor Story of the Boston Red Sox should be in your lineups. In a close victory against the Blue Jays, Story went 1-5 with a double and a strikeout. 

Story has been having a strong season for the Red Sox, and could play well again, against the Blue Jays. Fantasy players could see a multi-RBI game from the Red Sox veteran slugger at Toronto. 

1B Michael Busch, New York Mets at Chicago Cubs ($4,700 – DraftKings/3,100-Fanduel)

Michael Busch of the Chicago Cubs should be in Wednesday night’s top MLB DFS lineups for fantasy players. In the Cubs’ loss against the Mets, Busch went 0-3 with a walk and a strikeout

Busch has been having a breakout season for the Cubs and could have a strong performance against the Mets tonight. Fantasy players could see a multi-RBI game from the Cubs veteran slugger against the Mets’ pitching staff tonight. 

2B/OF Tommy Edman, Los Angeles Dodgers at Arizona Diamondbacks ($3,900 – DraftKings/2,900-Fanduel)

The last player to have for your fantasy lineups is Tommy Edman, of the Los Angeles Dodgers, in tonight’s top MLB DFS lineups. In a walk-off loss against the Diamondbacks, Edman went 0-4 with two strikeouts. 

Edman has been sluggish this September, but could have a bounce-back game against the Diamondbacks tonight. Fantasy players could see a multi-hit game with a home run from the Dodgers veteran utility player. 

September 24th Top MLB DFS Benchwarmers 

3B Addison Barger, Boston Red Sox at Toronto Blue Jays ($4,400 – DraftKings/3,000-Fanduel)

Addison Barger is the first player who should be on your top MLB DFS fantasy benches for Wednesday night’s games. In the loss against the Red Sox, Barger went 0-4 during the brutal loss at home against their division rivals.

 Barger has been struggling in the last week with one hit in his last six games. Fantasy players could see another hitless game, along with multiple strikeouts, from the Blue Jays’ emerging star infielder tonight. 

OF Corbin Carroll, Los Angeles Dodgers at Arizona Diamondbacks ($6,100 – DraftKings/4,400-Fanduel)

Corbin Carroll of the Arizona Diamondbacks is another player who should be on your fantasy bench in tonight’s Top MLB DFS lineups. In the walk-off win against the Dodgers, Carroll went 1-3 with two strikeouts and a walk. 

Carroll has been playing well this season, but could have a poor performance against the Dodgers’ pitching tonight. Fantasy players could see a multi-strikeout game from the Diamondbacks superstar against the Dodgers. 

OF Juan Soto, New York Mets at Chicago Cubs ($6,200 – DraftKings/4,300-Fanduel) 

Juan Soto of the New York Mets should be the last player on your top MLB DFS bench for Wednesday night’s games. In the comeback win against the Cubs, Soto went 1-4 with a walk, a strikeout, and a stolen base. 

Soto has been having a stellar season for the Mets, but could have a weak game against the Cubs tonight. Fantasy players could see a hitless game from the Mets’ superstar against the Cubs. 

Total Apex Media Stack Of The Day

Sep 23, 2025; Toronto, Ontario, CAN; Boston Red Sox first baseman Nathaniel Lowe (37) and relief pitcher Aroldis Chapman (44) celebrate a win over the Toronto Blue Jays at Rogers Centre. Mandatory Credit: Dan Hamilton-Imagn Images

Wednesday’s top MLB DFS stack should be the Boston Red Sox, Jarren Duran, Wilyer Abreu, and Nathaniel Lowe. The Red Sox are trying their best to survive in September for a playoff spot, and could have a great game against the Blue Jays tonight. Fantasy players could see a great game from the Red Sox lineup against the Blue Jays to keep the week going for tonight’s top MLB DFS lineups and fantasy stacks. 

The first player for tonight’s top MLB DFS stack of the night is Duran, who could have a great game against the Blue Jays. In the win against the Blue Jays, Duran went 0-5 with three strikeouts. Duran has been struggling, but could have a bounce-back game against the Blue Jays with their playoff lives on the line this week. Fantasy players could see Duran have a multi-hit game from the Red Sox veteran outfielder tonight and win cash prizes. 

Another player who could have a great game against the Blue Jays for fantasy lineups is Abreu, who could have a great game tonight. In the close win against the Blue Jays, Abreu went 1-3 with a double and a run. Abreu, even with returning from the IL, is having a strong game against the Blue Jays with a great performance tonight. Fantasy players could see a home run from the Red Sox veteran star against the Blue Jays and win cash prizes. 

The last player for tonight’s top MLB DFS stack should be Lowe, who could have a great performance against the Blue Jays tonight. In the win against the Blue Jays at Toronto, Lowe went 2-2 with a run, two RBIs, and two walks. Lowe has been having a strong stint with the Red Sox since getting picked up by them, and could have a strong game tonight. Fantasy players could see another multi-RBI game from the Red Sox veteran slugger against the Blue Jays tonight. With the MLB season ending next week, fantasy players could win cash prizes with tonight’s top MLB DFS lineups and stacks. 

This article first appeared on Total Apex Fantasy Sports and was syndicated with permission.

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