49ers Activate Yetur Gross-Matos From IR

Gross-Matos returned to practice on December 10. He was not activated in time to play in Week 15, but enough progress has been made during the past few days for a return to action to take place tonight. The 27-year-old has been sidelined since Week 5 due to a hamstring injury.

When Gross-Maros aggravated the ailment, his return timeline was set back. That led to his IR placement and left the former second-rounder unavailable for an extended period. Getting him back in the fold will be a welcomed development on a San Francisco team which has been hit hard by injuries in 2025. The defensive end spot in particular has been thinned out over the course of the year.

Starters Nick Bosa and Mykel Williams are each recovering from ACL tears. Neither will be able to return in 2025, something which has led to the likes of Bryce Huff, Sam Okuayinonu and Clelin Ferrell taking on increased roles. The team was linked to Trey Hendrickson ahead of the trade deadline, but the only acquisition on that front was Keion White. Getting Gross-Matos back in the fold will provide depth along the edge, although the Penn State product has starting experience dating back to his Panthers tenure.

A 2024 free agent addition, Gross-Matos played 11 games during his debut San Francisco campaign. He notched four sacks in that span, the second-highest total of his career. Chipping in down the stretch and into the playoffs would be key for the 49ers; it would also help boost Gross-Matos’ value on the open market for 2026.

Given today’s move, San Francisco has three IR activations remaining for the regular season. The team will receive another two once the playoffs begin.