49ers vs. Cowboys in Week 10: Preview plus odds

The San Francisco 49ers head back on the road to take on the Dallas Cowboys at AT&T Stadium. This matchup marks the 42nd all-time meeting between the two teams and the first time the 49ers have traveled to Dallas for a regular-season game since 2020. San Francisco looks to earn its third consecutive victory against the Cowboys and improve to 22-19-1 all-time against Dallas.

Previous game

The 49ers are coming off a 38-17 victory over the Las Vegas Raiders. San Francisco's offense recorded a season-high 190 rushing yards and was led by QB Brock Purdy, who completed 17 of 25 pass attempts for 232 yards and two touchdowns while adding seven carries for a season-high 40 yards and one touchdown on the ground.

RB Christian McCaffrey recorded 18 carries for 68 yards and one touchdown, plus two receptions for 19 yards and a 12-yard touchdown reception. WR Jordan Watkins added four receptions for a team- and career-high 86 yards and his first career touchdown.

Defensively, the 49ers forced five turnovers. LB Dre Greenlaw led the way with a team-high eight tackles and one fumble recovery, while LB Fred Warner recorded five tackles, one forced fumble and one fumble recovery. LB Jaden Dugger added four tackles and an interception, which he returned 35 yards for a touchdown. CB Renardo Green and S Malik Mustapha each recorded an interception, while CB Upton Stout added four tackles, one pass defensed and one forced fumble.

The 49ers Communications staff provided the above breakdown.

Below is everything you need to know to follow the upcoming game.

When does the game start?

Sunday, November 15 at 1:25 p.m. PT

Where is the game being played?

AT&T Stadium in Arlington, Texas

Who are the head coaches?

49ers: Kyle Shanahan
Cowboys: Brian Schottenheimer

Betting Odds

As of November 11, the 49ers are favored by four points, with an over/under set at 55.5 points, per BetMGM.

What channel is the game on?

Network: FOX
Play-By-Play: Kevin Burkhardt
Color Analyst: Tom Brady
Sideline Reporter: Erin Andrews
Sideline Reporter: Tom Rinaldi

What areas will receive the broadcast?

The broadcast will be viewable nationally on FOX. It is the only late game currently scheduled on the network.

Where can I stream the game?

Fans can stream the game using the FOX Sports app, FOXSports.com, or using FOX One (subscription).

NFL Sunday Ticket subscribers can stream the game using the YouTube TV app. Those who purchased through YouTube Premium can watch via the YouTube app. Additionally, NFL+ subscribers can stream the game in its entirety once the matchup is completed.

Bay Area fans can stream the game through the official 49ers app or at 49ers.com.

Where can I listen to the radio broadcast?

49ers Radio
Bay Area fans can listen on KGO 810 AM and The Bone 107.7 FM, where Guy Haberman and Tim Ryan will call the game.

Jesús Zárate and Carlos Yustis will call the game in Spanish. Fans can listen at 49ers.com/esp.

Cowboys Radio
Dallas area fans can listen on KRLD-FM 105.3 The Fan, where Brad Sham and Babe Laufenberg will call the game.

National Radio
Fans can listen to the game on Compass Media, where Ted Emrich and Steve Beuerlein will call the game.

Streaming
NFL+ subscribers can listen to the game through that service.

Game discussion

Fans can discuss the game within our Niner Talk forum.

How has this series played out historically?

Matchups: 41
Series Record: 49ers lead series 21-19-1
49ers Home Record vs. Cowboys: 49ers lead series 12-10
49ers Away Record vs. Cowboys: Series is tied 9-9-1
First Meeting: 11/20/60, 49ers win 26-14, at Dal.
Last Meeting: 10/27/24, 49ers win 30-24, at SF
Current Streak: Won 4
Longest 49ers Win Streak: 6 (10/11/81 – 11/11/90)
Longest Cowboys Win Streak: 5 (12/23/72 – 10/12/80)
Most 49ers Points: 45 (10/11/81): 49ers win 45-14, at SF
Most Cowboys Points: 59 (10/12/80): Cowboys win 59-14, at Dal.
49ers Shutouts: None
Cowboys Shutouts: None

49ers Notes

• QB Brock Purdy completed 17 of 25 attempts (68%) for 232 yards and two touchdowns with a 107.4 passer rating. He also rushed for 40 yards and a touchdown in Week 9. Ranks third with a 109.8 passer rating this season. Aims for his ninth consecutive game with a touchdown pass. Passed for 260 yards and a touchdown and added a rushing touchdown in the last meeting. Aims for his third consecutive game against Dallas with 250+ passing yards, a touchdown pass, and a 110+ passer rating.
• RB Christian McCaffrey recorded 87 scrimmage yards (68 rushing, 19 receiving) and two touchdowns (one rushing, one receiving) in Week 9. Has 37 career receiving touchdowns, the most by a running back in the Super Bowl era. Ranks second with 13,706 scrimmage yards (8,046 rushing, 5,660 receiving) since 2017. Ranks tied for third with 10 scrimmage touchdowns this season. Aims for his fifth consecutive game with 80+ scrimmage yards and eighth consecutive game with a touchdown.
• WR Jordan Watkins had four catches for a career-high 86 receiving yards and recorded his first career touchdown reception in Week 9.
• WR Keenan Allen could make his San Francisco debut. Ranks eighth all-time with 1,095 receptions.
• TE George Kittle had four catches for 58 yards in Week 9. Has recorded 50+ receiving yards in six of his past seven games. Ranks third among tight ends with 483 receiving yards, tied for fourth with five touchdown receptions, and tied for fifth with 38 receptions in 2026.
• DL Nick Bosa recorded a tackle for loss in Week 9 and aims for his fourth consecutive road game with a tackle for loss. Aims for his third consecutive game with 0.5+ sacks against Dallas.
• DL DeForest Buckner has recorded a tackle for loss in six of his past seven road games.
• LB Dre Greenlaw led the team with eight tackles and recorded three tackles for loss and a fumble recovery in Week 9. Has recorded 8+ tackles in five of his past six games.
• LB Fred Warner had five tackles, a tackle for loss, a forced fumble, and a fumble recovery last week. Aims for his third consecutive game with a forced fumble. Ranks tied for first with five forced fumbles this season.
• LB Jaden Dugger recorded his first career interception returned for a touchdown in Week 9. He is one of two rookies (along with Josiah Trotter) with an interception returned for a touchdown this season.
• DL Osa Odighizuwa recorded 216 tackles, 17 sacks, 34 tackles for loss, and two forced fumbles with Dallas from 2021-25.
• CB Renardo Green recorded an interception last week and ranks tied for third with four interceptions in 2026.
• S Malik Mustapha recorded his first interception of the season in Week 9. Has recorded a pass defensed in four of his past five games.

Cowboys Notes

• QB Dak Prescott passed for 335 yards and two touchdowns with a 114.2 passer rating in Week 9. Aims for his 10th consecutive game with a touchdown pass and fourth consecutive game with a 95+ passer rating. Has thrown for 275+ yards in three of his past four home games. Passed for 243 yards and two touchdowns in the last meeting. Aims for his fifth consecutive game against San Francisco with a touchdown pass.
• RB Javonte Williams recorded 124 scrimmage yards (101 rushing, 23 receiving) and a rushing touchdown in Week 9. Has recorded a rushing touchdown in six of his past seven games and in two of his past three home games. Had 58 rushing yards in the last meeting.
• RB Tyler Goodson rushed for a season-high 77 yards in Week 9.
• WR CeeDee Lamb led the team with 10 receptions for a season-high 195 yards and a touchdown in Week 9. Has 641 career receptions, the most by a player under age 28 in NFL history. Has recorded 70 receptions for 904 yards this season and is the first player in NFL history with 70+ catches and 900+ receiving yards in each of his first seven career seasons. Ranks second with 904 receiving yards and tied for second with seven touchdown receptions this season. Has a touchdown catch in two of his past three games. Had 13 catches for 146 yards and two touchdowns in the last meeting. Has recorded 85+ receiving yards in two of his past three games against San Francisco.
• TE Jake Ferguson recorded his fourth touchdown reception of the season last week.
• DT Quinnen Williams led the team with seven tackles and recorded three tackles for loss and a forced fumble in Week 9. Has recorded a sack in three of his past four games. Aims for his third consecutive game with 7+ tackles.
• LB Rashan Gary had six tackles, a sack, and two tackles for loss in Week 9. Aims for his third consecutive game against San Francisco with 0.5+ sacks.
• LB Shemar James had five tackles and a fumble recovery last week. Aims for his fourth consecutive game with 5+ tackles.
• DB Caleb Downs (rookie) recorded a sack, an interception, and two passes defensed in Week 9. Ranks second among all rookie defensive backs with 49 tackles this season.
• CB DaRon Bland recorded a pass defensed in Week 9 and has one in four of his past five games.
• S P.J. Locke recorded a season-high two passes defensed in Week 9. Had a forced fumble in his last game against San Francisco (Sept. 25, 2022, with Denver).