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49ers vs. Raiders: Brock Purdy, several other starters set to play in Las Vegas

Originally posted on 49ers Webzone | By David Bonilla | Last updated Aug 16, 2025 3:32 PM ET

The San Francisco 49ers are rolling out their starters this afternoon, with quarterback Brock Purdy expected to take the field when the team faces the Las Vegas Raiders at Allegiant Stadium.

Most of San Francisco's starters sat out last weekend's preseason opener against the Denver Broncos, but this time several key players are suited up and ready to go.

#49ers Brock Purdy in uniform during warmups about 45 minutes before kickoff. It appears he'll make his 2025 preseason debut.— Eric Branch (@Eric_Branch) August 16, 2025

Eric Branch of the San Francisco Chronicle reported that George Kittle, Kyle Juszczyk, Ricky Pearsall, and Deommodore Lenoir are also among the starters preparing to play.

Earlier this week, head coach Kyle Shanahan confirmed he wanted his first-teamers to see action in the second preseason game.

"I'd like Brock to play," Shanahan admitted. "We'll see how it goes. I haven't decided anything for sure yet. We'll watch this tape. I planned on getting these starters going. There might be a couple of guys I rest, but there's not a lot of—especially on the defense—healthy starters as it is. ... But planning on some starters to play."

Notably, four of the 49ers' biggest names—Christian McCaffrey, Nick Bosa, Fred Warner, and Trent Williams—remain sidelined. However, with their track records, the veterans probably don't need preseason snaps to be ready for Week 1.

LT Trent Williams, LB Fred Warner, DE Nick Bosa being kept out -- as they should -- of this 49ers preseason game vs Raiders— Cam Inman (@CamInman) August 16, 2025